Bellavía S L, Sanz E G, Sereno R, Vermouth N T
Cátedras de Quimica Biológica, Facultades de Odontologia & Ciencias Médicas, Universidad Nacional de Córdoba, Argentina.
Arch Oral Biol. 1992;37(5):429-33. doi: 10.1016/0003-9969(92)90028-7.
The circadian rhythm of alpha-amylase, E.C. 3.2.1.1. alpha-1,4-glucan-4-glucanohydrolase) in the parotid glands of 25-day-old rats were studied under different experimental designs (fasting, reversed photoperiod, constant lighting conditions and treatment with reserpine and alpha-methyl-p-tyrosine). The rhythm of fasted rats did not change. There were modifications in the rhythm of rats submitted to a reversed photoperiod or treated with reserpine or alpha-methyl-p-tyrosine. The rhythm was present, with changes in the acrophase, in parotids of rats kept during their gestation and postnatal life in constant light or dark. Results suggest that the circadian rhythm of alpha-amylase in parotid gland of young rats is endogenous, synchronized by the photoperiod, and with maternal coordination.
在不同实验设计(禁食、颠倒光周期、持续光照条件以及用利血平和α-甲基对酪氨酸处理)下,研究了25日龄大鼠腮腺中α-淀粉酶(E.C. 3.2.1.1.α-1,4-葡聚糖-4-葡聚糖水解酶)的昼夜节律。禁食大鼠的节律没有变化。处于颠倒光周期或用利血平或α-甲基对酪氨酸处理的大鼠的节律有改变。在妊娠和出生后生活期间处于持续光照或黑暗环境中的大鼠腮腺中,该节律存在,且有峰相位的变化。结果表明,幼鼠腮腺中α-淀粉酶的昼夜节律是内源性的,受光周期同步,并存在母体协调作用。