Sears Samuel F, Serber Eva R, Alvarez Luis G, Schwartzman David S, Hoyt Robert H, Ujhelyi Michael R
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610, USA.
Pacing Clin Electrophysiol. 2005 Aug;28(8):801-7. doi: 10.1111/j.1540-8159.2005.00171.x.
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with a variety of symptoms such as dizziness, palpitations, shortness of breath, and other signs of heart failure, which in turn impact quality of life (QOL). Implantable cardioverter defibrillators with atrial therapies (ICDs-ATs) have been shown to reduce AF symptoms and improve QOL in select AF samples.
This study examined the strength of relationships between objective (device-detected AF events) versus subjective (emotional symptoms) data and AF symptoms (number) reported as part of the Patient Atrial Shock Survey of Acceptance and Tolerance Study (N = 96, 72% men, M age = 65, SD = 12). Depression and anxiety were assessed via the Center for Epidemiological Studies--Depression Scale and the-State Trait Anxiety Inventory. AF disease burden was measured via a number of device-detected AF episodes and the Atrial Tachyarrhythmia Symptom Severity Scale.
Hierarchical multiple regression analysis indicated that negative emotions accounted for a significant 13.2% of unique variance in AF symptom score (F change (1, 54) = 9.625, P = 0.003). On the other hand, the number of device-detected AF episodes accounted for non-significant 8.2% of unique variance in the AF symptom score (P = 0.167). The full model explained 25.7% of the variance in AF symptom score (F(6, 54) = 3.110, P = 0.011). Specifically, greater number of treated AF episodes (beta= 0.251, P = 0.043) and higher levels of negative emotions (beta= 0.369, P = 0.003) predicted greater number of reported AF symptoms.
Therefore, psychological distress may be a significant confounding factor affecting patient's report of AF symptoms rather than the actual experience of recurrent AF episodes.
心房颤动(AF)是最常见的心律失常,与多种症状相关,如头晕、心悸、呼吸急促以及其他心力衰竭症状,这些症状进而会影响生活质量(QOL)。已证实,带有心房治疗功能的植入式心脏复律除颤器(ICDs - ATs)可减轻AF症状并改善特定AF样本的生活质量。
本研究调查了作为患者心房电击接受与耐受性研究(N = 96,72%为男性,平均年龄 = 65岁,标准差 = 12)一部分所报告的客观(设备检测到的AF事件)与主观(情绪症状)数据之间的关系强度以及AF症状数量。通过流行病学研究中心抑郁量表和状态 - 特质焦虑量表评估抑郁和焦虑情况。通过设备检测到的AF发作次数和房性快速心律失常症状严重程度量表测量AF疾病负担。
分层多元回归分析表明,负面情绪在AF症状评分的独特方差中占显著的13.2%(F变化(1, 54) = 9.625,P = 0.003)。另一方面,设备检测到的AF发作次数在AF症状评分的独特方差中占不显著的8.2%(P = 0.167)。完整模型解释了AF症状评分方差的25.7%(F(6, 54) = 3.110,P = 0.011)。具体而言,更多的治疗性AF发作次数(β = 0.251,P = 0.043)和更高水平的负面情绪(β = 0.369,P = 0.003)预示着报告的AF症状数量更多。
因此,心理困扰可能是影响患者报告AF症状的一个重要混杂因素,而非复发性AF发作的实际体验。