Murray R W, Marotti K R
Molecular Biology Research, Upjohn Laboratories, Kalamazoo, MI 49001.
Biochim Biophys Acta. 1992 Jun 15;1131(2):207-10. doi: 10.1016/0167-4781(92)90079-f.
The cynomolgus monkey (Macaca fascicularis) apolipoprotein A-I (apo A-I) gene and corresponding flanking regions have been isolated from a cynomolgus monkey genomic library and completely sequenced. Comparison with the human sequence shows a greater than 90% homology with the monkey sequence, overall. The monkey apo A-I structural gene (1856 bp) is representative of the general apolipoprotein gene structure and consists of four exons and three introns. Minor differences exist between the monkey and human structural gene sequence but do not result in significant changes. Sequences preceding the putative monkey apo A-I promoter are virtually identical to the human apo A-I enhancer region with an exact match to the three enhancer DNA binding sites.
食蟹猴（Macaca fascicularis）载脂蛋白A-I（apo A-I）基因及其相应的侧翼区域已从食蟹猴基因组文库中分离出来并进行了全序列测定。与人类序列相比，总体上猴序列与之具有超过90%的同源性。猴apo A-I结构基因（1856 bp）代表了一般载脂蛋白基因结构，由四个外显子和三个内含子组成。猴与人的结构基因序列存在细微差异，但未导致显著变化。推测的猴apo A-I启动子之前的序列与人类apo A-I增强子区域几乎相同，与三个增强子DNA结合位点完全匹配。
