Karsenti Eric
Cell Biology and Biophysics Program, European Molecular Biology Laboratory, Heidelberg, Germany.
Mol Cell. 2005 Aug 19;19(4):431-2. doi: 10.1016/j.molcel.2005.08.002.
An Aurora A regulatory module has been identified in two different proteins: TPX2 in Xenopus laevis and TPXL-1 in C. elegans. The diverse roles of these two proteins in spindle assembly leave us to beckon the true C. elegans TPX2 ortholog to center stage.
在两种不同的蛋白质中发现了一种极光激酶A调节模块:非洲爪蟾中的TPX2和秀丽隐杆线虫中的TPXL-1。这两种蛋白质在纺锤体组装中的不同作用让我们去召唤真正的秀丽隐杆线虫TPX2直系同源物登上舞台中央。