单侧眼球摘除术会改变大鼠视交叉上核中血管活性肠肽样免疫反应性。
Unilateral enucleation alters vasoactive intestinal polypeptide-like immunoreactivity in the suprachiasmatic nucleus of the rat.
作者信息
Laemle L K
机构信息
Department of Anatomy, UMDNJ-New Jersey Medical School, Newark 07103.
出版信息
Brain Res. 1992 Feb 14;572(1-2):325-8. doi: 10.1016/0006-8993(92)90494-t.
PMID:1611531
Abstract
Adult Sprague-Dawley rats were unilaterally enucleated under deep anesthesia and sacrificed 3-11 months post-operatively. The brains were removed and the suprachiasmatic nuclei were evaluated for vasoactive intestinal polypeptide (VIP)-like immunoreactivity. Our data show that expression of VIP is reduced in the nucleus that is deprived of retinal input.
摘要
成年Sprague-Dawley大鼠在深度麻醉下进行单侧眼球摘除，并在术后3至11个月处死。取出大脑，评估视交叉上核的血管活性肠肽（VIP）样免疫反应性。我们的数据表明，在缺乏视网膜输入的核中，VIP的表达减少。
Zotero 插件