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痉挛型脑瘫患儿脑可塑性的神经生理学和神经影像学研究

Neurophysiologic and neuroimaging studies of brain plasticity in children with spastic cerebral palsy.

作者信息

Kułak Wojciech, Sobaniec Wojciech, Kuzia Joanna-Smigielska, Boćkowski Leszek

机构信息

Department of Pediatric Neurology and Rehabilitation, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, Poland.

出版信息

Exp Neurol. 2006 Mar;198(1):4-11. doi: 10.1016/j.expneurol.2005.11.014. Epub 2006 Jan 18.

DOI:10.1016/j.expneurol.2005.11.014
PMID:16414042
Abstract

Patients with cerebral palsy (CP) may have some problems other than this motor impairment: mental retardation, epilepsy and sensory disturbance. Healthy children and children with CP have an enhanced capacity for learning and memory compared to adults. There are few tools for brain plasticity investigations. The utility of the neurophysiologic and MRI techniques in the determination of brain reorganization and repair in patients with cerebral palsy is described. The authors discuss their results of quantitative EEG and spectroscopy MRI studies in children with CP. Quantitative EEG and spectroscopy MRI can be useful tools in the determination of these processes in children with CP.

摘要

脑瘫(CP)患者除了运动障碍外可能还有其他一些问题:智力迟钝、癫痫和感觉障碍。与成年人相比,健康儿童和脑瘫患儿具有更强的学习和记忆能力。用于脑可塑性研究的工具很少。本文描述了神经生理学和MRI技术在确定脑瘫患者脑重组和修复方面的效用。作者讨论了他们对脑瘫患儿进行定量脑电图和磁共振波谱研究的结果。定量脑电图和磁共振波谱可作为确定脑瘫患儿这些过程的有用工具。

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