Breier T
Klinik und Poliklinik für MKG-Chirurgie der Westf. Wilhelms-Universität, Münster.
Dtsch Zahnarztl Z. 1992 Jan;47(1):50-3.
For the conservative treatment of mandibular fractures with arch bars under local anaesthesia we used two forms of premedication in 140 patients: 1. an analgetic sedation with pethidine 1 mg/kg body weight and promethazine 0.5 mg/kg body weight i.m. (n = 70 cases) 2. an anxiolytic sedation with midazolam 0.05-0.1 mg/kg body weight i.v. (n = 70 cases). The effect of the premedication was measured retrospectively by the mean amount of local anaesthetics used during splinting. It could be noted that the mean consumption of local anaesthetics was significantly lower in the midazolam-group than in the pethidine/promethazine-group. The postoperative subjective assessment of the operation by the patients is better under anxiolytic than under analgetic sedation, too.
对于在局部麻醉下使用牙弓夹板保守治疗下颌骨骨折的情况，我们在140例患者中采用了两种术前用药形式：1. 肌肉注射哌替啶1mg/kg体重和异丙嗪0.5mg/kg体重进行镇痛镇静（n = 70例）；2. 静脉注射咪达唑仑0.05 - 0.1mg/kg体重进行抗焦虑镇静（n = 70例）。通过夹板固定期间使用的局部麻醉药平均用量对术前用药效果进行回顾性测量。可以注意到，咪达唑仑组局部麻醉药的平均消耗量显著低于哌替啶/异丙嗪组。患者对手术的术后主观评估在抗焦虑镇静下也比在镇痛镇静下更好。
