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Vitamin E and prostate cancer: is vitamin E succinate a superior chemopreventive agent?

作者信息

Basu Arpita, Imrhan Victorine

机构信息

Department of Nutrition and Food Sciences, Texas Woman's University, P.O. Box 425888, Denton, TX 76204-5888, USA.

出版信息

Nutr Rev. 2005 Jul;63(7):247-51. doi: 10.1111/j.1753-4887.2005.tb00380.x.

Abstract

There is convincing evidence that vitamin E succinate significantly reduces human prostate cancer growth in experimental models compared with alpha-tocopherol or tocopheryl acetate. Its intact delivery to cancer cells is questionable when administered orally; however, a study in transgenic mice showed a synergistic inhibitory effect of dietary vitamin E succinate, selenium, and lycopene on prostate cancer incidence. Clinical trials have yet to confirm this effect.

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