马占相思和大叶相思心材提取物的抗真菌和抗氧化活性比较。

Comparison of antifungal and antioxidant activities of Acacia mangium and A. auriculiformis heartwood extracts.

作者信息

Mihara Rie, Barry Karen M, Mohammed Caroline L, Mitsunaga Tohru

机构信息

Faculty of Bioresources, Department of Environment Science and Engineering, Mie University, 1515 Kamihama, Tsu 514-8507, Japan.

出版信息

J Chem Ecol. 2005 Apr;31(4):789-804. doi: 10.1007/s10886-005-3544-x.

DOI:10.1007/s10886-005-3544-x

PMID:16124251

Abstract

The effect of heartwood extracts from Acacia mangium (heartrot-susceptible) and A. auriculiformis (heartrot-resistant) was examined on the growth of wood rotting fungi with in vitro assays. A. auriculiformis heartwood extracts had higher antifungal activity than A. mangium. The compounds 3,4',7,8-tetrahydroxyflavanone and teracacidin (the most abundant flavonoids in both species) showed antifungal activity. A. auriculiformis contained higher levels of these flavonoids (3.5- and 43-fold higher, respectively) than A. mangium. This suggests that higher levels of these compounds may contribute to heartrot resistance. Furthermore, both flavonoids had strong 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and laccase inhibition. This suggests that the antifungal mechanism of these compounds may involve inhibition of fungal growth by quenching of free radicals produced by the extracellular fungal enzyme laccase.

摘要

通过体外试验研究了马占相思（易患心材腐朽）和大叶相思（抗心材腐朽）心材提取物对木材腐朽真菌生长的影响。大叶相思心材提取物的抗真菌活性高于马占相思。化合物3,4',7,8 - 四羟基黄烷酮和特曲菌素（两种树种中含量最高的黄酮类化合物）表现出抗真菌活性。大叶相思中这些黄酮类化合物的含量（分别高出3.5倍和43倍）高于马占相思。这表明这些化合物的较高含量可能有助于抗心材腐朽。此外，这两种黄酮类化合物都具有较强的1,1 - 二苯基 - 2 - 苦基肼（DPPH）自由基清除活性和漆酶抑制作用。这表明这些化合物的抗真菌机制可能涉及通过淬灭细胞外真菌酶漆酶产生的自由基来抑制真菌生长。