Philipsen Alexandra, Feige Bernd, Hesslinger Bernd, Ebert Dieter, Carl Christine, Hornyak Magdolna, Lieb Klaus, Voderholzer Ulrich, Riemann Dieter
Department of Psychiatry and Psychotherapy, University of Freiburg Medical School, Germany.
Sleep. 2005 Jul;28(7):877-84. doi: 10.1093/sleep/28.7.877.
Previous studies in children with attention-deficit/hyperactivity disorder and attention deficit disorder (ADHD/ADD) have shown impaired sleep quality with increased nocturnal motor activity. However, polysomnographic findings are not unequivocal. Up to now, in adults with ADHD, only 1 case-control polysomnographic study with small sample size has been performed. We investigated objective and subjective sleep quality in adultADHD, including an electroencephalogram spectral power analysis.
Single-blind comparative study.
University medical center.
Twenty adult unmedicated ADHD patients without current comorbid major depression, drug abuse, or comorbid axis-II disorder and 20 sex- and age-matched control subjects.
N/A.
Conventional polysomnographic parameters and sleep electroencephalogram spectral power analysis was calculated for the 2 laboratory nights. Subjective sleep parameters were estimated by sleep questionnaires to assess the relationship between objective and subjective sleep measurements.
Adult ADHD patients showed increased nocturnal motor activity (as indicated by heightened indexes of periodic leg movements in sleep), which was significantly inversely correlated with subjective total sleep time. Although ADHD patients displayed significantly increased objective total sleep time, the subjective ratings documented impaired sleep quality in those with ADHD. Other polysomnographic sleep patterns and spectral electroencephalogram parameters did not differ between ADHD patients and normal controls.
Similar to children, adults with ADHD show increased nocturnal motor activity. Otherwise, sleep does not seem to be impaired in ADHD patients. However, the dissociation between objective and subjective sleep parameters points to a misinterpretation of sleep quality in patients with ADHD.
既往针对注意力缺陷/多动障碍及注意力缺陷障碍（ADHD/ADD）儿童的研究显示，睡眠质量受损，夜间运动活动增加。然而，多导睡眠图的结果并不明确。到目前为止，针对成人ADHD，仅进行过1项样本量较小的病例对照多导睡眠图研究。我们调查了成人ADHD患者的客观和主观睡眠质量，包括脑电图频谱功率分析。
单盲对照研究。
大学医学中心。
20名未用药的成年ADHD患者，目前无共病的重度抑郁症、药物滥用或共病的轴II障碍，以及20名性别和年龄匹配的对照者。
无。
在两个实验室夜晚计算常规多导睡眠图参数和睡眠脑电图频谱功率分析。通过睡眠问卷评估主观睡眠参数，以评估客观和主观睡眠测量之间的关系。
成年ADHD患者夜间运动活动增加（睡眠中周期性腿部运动指数升高表明），这与主观总睡眠时间显著负相关。虽然ADHD患者的客观总睡眠时间显著增加，但主观评分显示ADHD患者的睡眠质量受损。ADHD患者和正常对照者之间的其他多导睡眠图睡眠模式和脑电图频谱参数没有差异。
与儿童相似，成年ADHD患者夜间运动活动增加。除此之外，ADHD患者的睡眠似乎未受损。然而，客观和主观睡眠参数之间的分离表明ADHD患者对睡眠质量存在误解。
