De Schamphelaere Karel A C, Heijerick Dagobert G, Janssen Colin R
Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Jozef Plateaustraat 22, B-9000 Ghent, Belgium.
Ecotoxicol Environ Saf. 2006 Feb;63(2):189-95. doi: 10.1016/j.ecoenv.2005.07.012.
Short chronic 48-h toxicity tests with the freshwater rotifer Brachionus calyciflorus (Pallas) were conducted to assess the modifying effects of pH and natural dissolved organic carbon (DOC) concentration on reproductive toxicity of Cu. Toxicity tests were carried out in four test waters according to a 2 x 2 design, in which pH (6 and 7.8) and DOC (5 and 15 mg C/L) were the test variables. Concentrations of dissolved Cu with no observed effect at 48 h (NOEC) varied 12-fold between 8.2 and 103 microg/L. Higher DOC and higher pH resulted in a reduction of toxicity, which is in line with the concepts of the biotic ligand model (BLM). A chronic Cu-BLM, originally developed for the cladoceran Daphnia magna, was calibrated to the rotifer dataset and was found to be able to predict all rotifer NOECs with an error factor of less than 1.6. This finding may be of great interest for risk assessment and the establishment of water quality criteria, as it suggests that chronic Cu-BLMs are comparable across phyla (i.e., arthropoda to rotifera).
开展了为期48小时的淡水萼花臂尾轮虫（Brachionus calyciflorus (Pallas)）短期慢性毒性试验，以评估pH值和天然溶解有机碳（DOC）浓度对铜生殖毒性的调节作用。根据2×2设计在四种试验水体中进行毒性试验，其中pH值（6和7.8）和DOC（5和15毫克碳/升）为试验变量。48小时无观察效应浓度（NOEC）的溶解铜浓度在8.2至103微克/升之间变化了12倍。较高的DOC和较高的pH值导致毒性降低，这与生物配体模型（BLM）的概念一致。最初为大型枝角类水蚤（Daphnia magna）开发的慢性铜生物配体模型针对轮虫数据集进行了校准，发现能够以小于1.6的误差因子预测所有轮虫的NOEC。这一发现可能对风险评估和水质标准的制定具有重要意义，因为它表明慢性铜生物配体模型在不同门（即节肢动物到轮虫）之间具有可比性。
