Kouides P A, Bennett J M
Department of Medicine, University of Rochester School of Medicine and Dentistry, New York.
Hematol Oncol Clin North Am. 1992 Jun;6(3):485-99.
The FAB classification has provided a common language for clinicians and pathologists in the investigation of myelodysplasia. It has also provided prognostic information, given the excellent correlation between FAB subgroup and survival (see Table 2). Refinements in immunologic and cytogenetic typing should provide further prognostic power and correlation with the underlying biologic processes.
FAB分类为临床医生和病理学家在骨髓增生异常综合征的研究中提供了一种通用语言。鉴于FAB亚组与生存率之间具有良好的相关性(见表2),它还提供了预后信息。免疫分型和细胞遗传学分型的改进应能提供更强的预后预测能力,并与潜在的生物学过程建立相关性。