男性职业性热暴露对受孕时间的影响。

Effect of male occupational heat exposure on time to pregnancy.

作者信息

Thonneau P, Ducot B, Bujan L, Mieusset R, Spira A

机构信息

Department of Epidemiology, Public Health and Human Reproduction, INSERM, Paris, France.

出版信息

Int J Androl. 1997 Oct;20(5):274-8. doi: 10.1046/j.1365-2605.1997.d01-303.x.

DOI:10.1046/j.1365-2605.1997.d01-303.x

PMID:16130271

Abstract

The relationship between male occupational heat exposure and the time required to achieve a pregnancy [TTP] was studied in a retrospective survey of 402 fertile couples. The TTP for t he subgroups 'exposure t o heat' (median = 4 .0 months; mean 11.8; SD = 13.3) and 'professional driver >3 h/day' (median = 4.5; mean = 14.4; SD = 28.5) was significantly longer (both p < 0.05) than for the controls (median = 2.8; mean = 7.8; SD = 13.3). Bakers and welders showed comparable results: only 14% of the bakers' partners became pregnant within 3 months (cf. 55% of controls, p < 0.05) and only 29% became pregnant within 6 months (cf. 74% of controls, p < 0.02). This study suggests that occupational exposure to heat is a 'weak' risk factor for male subfertility.

摘要

在一项对402对可育夫妇的回顾性调查中，研究了男性职业性热暴露与实现妊娠所需时间（TTP）之间的关系。“热暴露”亚组（中位数=4.0个月；均值11.8；标准差=13.3）和“每天驾车超过3小时的职业司机”亚组（中位数=4.5；均值=14.4；标准差=28.5）的TTP显著长于对照组（中位数=2.8；均值=7.8；标准差=13.3）（p均<0.05）。面包师和焊工的结果类似：面包师伴侣中只有14%在3个月内怀孕（对照组为55%，p<0.05），只有29%在6个月内怀孕（对照组为74%，p<0.02）。这项研究表明，职业性热暴露是男性生育力低下的一个“微弱”风险因素。