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DNase and atelectasis in non-cystic fibrosis pediatric patients.非囊性纤维化儿科患者中的脱氧核糖核酸酶与肺不张
Crit Care. 2005 Aug;9(4):R351-6. doi: 10.1186/cc3544. Epub 2005 May 20.
2
The yield of flexible fiberoptic bronchoscopy in pediatric intensive care patients.小儿重症监护患者中可弯曲纤维支气管镜检查的成功率
Chest. 2004 Oct;126(4):1353-9. doi: 10.1378/chest.126.4.1353.
3
Fluorocarbons facilitate lung recruitment.碳氟化合物有助于肺复张。
Intensive Care Med. 2003 Dec;29(12):2297-2302. doi: 10.1007/s00134-003-1881-1. Epub 2003 Sep 13.
4
PEEP decreases atelectasis and extravascular lung water but not lung tissue volume in surfactant-washout lung injury.在表面活性剂冲洗性肺损伤中,呼气末正压(PEEP)可减少肺不张和血管外肺水,但不会减少肺组织容量。
Intensive Care Med. 2003 Nov;29(11):2026-33. doi: 10.1007/s00134-003-1906-9. Epub 2003 Jul 25.
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Ventilator-associated pneumonia and atelectasis: evaluation through bronchoalveolar lavage fluid analysis.呼吸机相关性肺炎和肺不张:通过支气管肺泡灌洗术分析进行评估
Intensive Care Med. 2003 Apr;29(4):555-63. doi: 10.1007/s00134-003-1680-8. Epub 2003 Feb 21.
6
Atelectasis: mechanisms, diagnosis and management.肺不张:机制、诊断与管理
Paediatr Respir Rev. 2000 Sep;1(3):274-8. doi: 10.1053/prrv.2000.0059.
7
Do bronchodilators have an effect on bronchiolitis?支气管扩张剂对细支气管炎有作用吗?
Crit Care. 2002 Apr;6(2):111-2. doi: 10.1186/cc1466. Epub 2002 Mar 11.
8
Efficacy of recombinant human deoxyribonuclease I in the hospital management of respiratory syncytial virus bronchiolitis.重组人脱氧核糖核酸酶I在呼吸道合胞病毒细支气管炎医院管理中的疗效。
Chest. 2001 Jul;120(1):203-8. doi: 10.1378/chest.120.1.203.
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[Surfactant--treatment of complete lobar atelectasis after exacerbation of bronchial asthma by infection].[表面活性剂——治疗感染所致支气管哮喘加重后全叶肺不张]
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Types and mechanisms of pulmonary atelectasis.肺不张的类型及机制
J Thorac Imaging. 1996 Spring;11(2):92-108. doi: 10.1097/00005382-199621000-00002.

肺不张的治疗:证据何在?

Treatment of atelectasis: where is the evidence?

作者信息

Schindler Margrid B

机构信息

Paediatric Intensive Care Unit, Bristol Royal Hospital for Children, Bristol, UK.

出版信息

Crit Care. 2005 Aug;9(4):341-2. doi: 10.1186/cc3766. Epub 2005 Jul 7.

DOI:10.1186/cc3766
PMID:16137380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1269473/
Abstract

Lobar atelectasis is a common problem caused by a variety of mechanisms including resorption atelectasis due to airway obstruction, passive atelectasis from hypoventilation, compressive atelectsis from abdominal distension and adhesive atelectasis due to increased surface tension. However, evidence-based studies on the management of lobar atelectasis are lacking. Examination of air-bronchograms on a chest radiograph may be helpful to determine whether proximal or distal airway obstruction is involved. Chest physiotherapy, nebulised DNase and possibly fibreoptic bronchoscopy might be helpful in patients with mucous plugging of the airways. In passive and adhesive atelectasis, positive end-expiratory pressure might be a useful adjunct to treatment.

摘要

肺叶不张是一个常见问题,由多种机制引起,包括气道阻塞导致的吸收性肺不张、通气不足引起的被动性肺不张、腹部膨胀导致的压迫性肺不张以及表面张力增加引起的粘连性肺不张。然而,缺乏关于肺叶不张管理的循证研究。胸部X光片上的空气支气管造影检查可能有助于确定是近端还是远端气道阻塞。胸部物理治疗、雾化脱氧核糖核酸酶以及可能的纤维支气管镜检查对气道黏液阻塞患者可能有帮助。在被动性和粘连性肺不张中,呼气末正压可能是治疗的有用辅助手段。