Baldeschi Lelio, MacAndie Kerr, Hintschich Christoph, Wakelkamp Iris M M J, Prummel Mark F, Wiersinga Wilmar M
Orbital Center, Department of Ophthalmology, University of Amsterdam, Amsterdam, The Netherlands.
Am J Ophthalmol. 2005 Oct;140(4):642-7. doi: 10.1016/j.ajo.2005.04.023. Epub 2005 Sep 2.
To evaluate the contribution of maximal removal of the deep lateral wall of the orbit to exophthalmos reduction in Graves' orbitopathy and its influence on the onset of consecutive diplopia.
Case-control study.
The medical records of two cohorts of patients affected by Graves' orbitopathy with exophthalmos > or = 23 mm, without preoperative diplopia, were retrieved at random from the pool of patients decompressed for rehabilitative reasons at our institution (01/1990 to 12/2003), and retrospectively reviewed. They had been treated with an extended (cases, group 1, n = 15) or conservative (controls, group 2, n = 15) 3-wall orbital decompression performed through a coronal approach. The deep portion of the lateral wall had been removed in the extended decompression group while preserved in the conservative decompression group. Demographics, preoperative characteristics, and surgical outcome were compared. The difference in mean exophthalmos reduction between groups 1 and 2 was considered to be the contribution of the deep lateral wall to reduction of exophthalmos.
Groups 1 and 2 were drawn from a pool of 37 and 335 patients, respectively. Demographics and preoperative characteristics of the two groups were not significantly different. The mean contribution of the deep lateral wall to exophthalmos reduction was 2.3 mm. The onset of consecutive diplopia was not significantly different between the two groups (case n = 2/15, controls n = 5/15; P = .203). Diplopia resolved spontaneously in all the patients of group 1, while all the patients of group 2 required surgery.
Removal of the deep lateral orbital wall as part of a coronal-approach, 3-wall decompression, enhances the degree of exophthalmos reduction without increasing the risk of consecutive diplopia.
评估眼眶外侧壁深层最大程度切除对Graves眼病眼球突出度降低的作用及其对连续性复视发生的影响。
病例对照研究。
从1990年1月至2003年12月间因康复原因在本机构接受减压治疗的患者中随机抽取两组Graves眼病患者的病历,这些患者眼球突出度≥23mm且术前无复视,并进行回顾性分析。两组患者均采用冠状入路行扩大(病例组,第1组,n = 15)或保守(对照组,第2组,n = 15)三壁眼眶减压术。扩大减压组切除了外侧壁深层部分,而保守减压组予以保留。比较两组患者的人口统计学资料、术前特征及手术结果。第1组和第2组平均眼球突出度降低值的差异被视为外侧壁深层对眼球突出度降低的作用。
第1组和第2组分别来自37例和335例患者。两组患者的人口统计学资料及术前特征无显著差异。外侧壁深层对眼球突出度降低的平均作用为2.3mm。两组连续性复视的发生率无显著差异(病例组n = 2/15,对照组n = 5/15;P = 0.203)。第1组所有患者的复视均自行缓解,而第2组所有患者均需手术治疗。
作为冠状入路三壁减压术一部分的眼眶外侧壁深层切除可提高眼球突出度降低程度,且不增加连续性复视的风险。