Gattoni M, Astolfi S, Tiberio R, Boldorini R, Pia F, Leigheb G
Clinique Dermatologique, Università del Piemonte Orientale A. Avogadro, Hopitâl Maggiore della Carità, Novara, Italie.
Ann Dermatol Venereol. 2005 Jun-Jul;132(6-7 Pt 1):540-3. doi: 10.1016/s0151-9638(05)79335-2.
Chordomas are rare extradural bone tumors arising from notochord remnants, the embryonic structure forming the original axis of the spine. They represent 0.1p. 100 of all intra-cranial tumors. The chordoma is a locally malignant cancer that tends to invade the surrounding tissues. Its localization in the skin is exceptional.
A 56 year-old man developed a nut-sized vegetating nodule on the nasal groove. This lesion appeared a few months following surgery for a frontoglabellar relapse of a chordoma that had developed six years earlier at the base of the skull.
We report this case because of the rareness of cutaneous involvement and the particular conditions in which it occurred. It may have been due to tumoral seeding during the previous surgical interventions.
脊索瘤是一种罕见的硬脊膜外骨肿瘤，起源于脊索残余，脊索是形成脊柱原始轴的胚胎结构。它们占所有颅内肿瘤的0.1%。脊索瘤是一种局部恶性肿瘤，倾向于侵犯周围组织。其发生于皮肤的情况极为罕见。
一名56岁男性在鼻沟处出现一个核桃大小的赘生性结节。该病变出现在因六年前发生于颅底的脊索瘤额眉间复发而进行手术几个月后。
我们报告该病例是因为皮肤受累情况罕见以及其发生的特殊情况。这可能是由于先前手术干预过程中的肿瘤播散所致。
