通过间隔寡核苷酸分型法对希腊结节病患者的结核分枝杆菌复合群分离株进行特征分析。
Characterization of Mycobacterium tuberculosis complex isolates from Greek patients with sarcoidosis by Spoligotyping.
作者信息
Gazouli M, Ikonomopoulos J, Koundourakis A, Bartos M, Pavlik I, Overduin P, Kremer K, Gorgoulis V, Kittas C
机构信息
Department of Histology-Embryology, School of Medicine, University of Athens, Greece.
出版信息
J Clin Microbiol. 2005 Sep;43(9):4858-61. doi: 10.1128/JCM.43.9.4858-4861.2005.
Abstract
Spoligotyping was undertaken with 38 Mycobacterium tuberculosis isolates from Greek sarcoidosis patients and 31 isolates from patients with tuberculosis. Fifty percent of the isolates from sarcoidosis patients and 16.13% of the isolates from patients with tuberculosis were represented by a unique pattern, whereas the remaining isolates belonged to seven shared types. Interestingly, half of the isolates from sarcoidosis patients did not resemble the spoligotypes of the isolates from patients with tuberculosis, most of which pertained to shared spoligotypes.
摘要
对来自希腊结节病患者的38株结核分枝杆菌分离株和来自结核病患者的31株分离株进行了间隔寡核苷酸分型。结节病患者分离株的50%和结核病患者分离株的16.13%表现为独特的模式，而其余分离株属于7种共享类型。有趣的是，结节病患者分离株中有一半与结核病患者分离株的间隔寡核苷酸分型不同，其中大多数属于共享的间隔寡核苷酸分型。
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