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本文引用的文献

1
Simultaneous detection and strain differentiation of Mycobacterium tuberculosis complex in paraffin wax embedded tissues and in stained microscopic preparations.石蜡包埋组织及染色显微镜标本中结核分枝杆菌复合群的同步检测与菌株鉴别
Mol Pathol. 1998 Aug;51(4):209-14. doi: 10.1136/mp.51.4.209.
2
Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology.同时检测结核分枝杆菌并进行菌株鉴别以用于诊断和流行病学研究。
J Clin Microbiol. 1997 Apr;35(4):907-14. doi: 10.1128/jcm.35.4.907-914.1997.
3
Predominance of a single genotype of Mycobacterium tuberculosis in countries of east Asia.东亚国家结核分枝杆菌单一基因型的优势地位。
J Clin Microbiol. 1995 Dec;33(12):3234-8. doi: 10.1128/jcm.33.12.3234-3238.1995.
4
Strain identification of Mycobacterium tuberculosis by DNA fingerprinting: recommendations for a standardized methodology.通过DNA指纹图谱技术进行结核分枝杆菌菌株鉴定：标准化方法建议
J Clin Microbiol. 1993 Feb;31(2):406-9. doi: 10.1128/jcm.31.2.406-409.1993.
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DNA restriction fragment analysis to define an extended cluster of tuberculosis in homeless men and their associates.DNA限制性片段分析以确定无家可归男性及其同伴中结核病的一个扩大聚集群。
J Infect Dis. 1993 Feb;167(2):490-4. doi: 10.1093/infdis/167.2.490.
6
Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis.结核分枝杆菌复合群菌株中插入序列的发生与稳定性：评估一种基于插入序列的DNA多态性作为结核病流行病学工具的作用。
J Clin Microbiol. 1991 Nov;29(11):2578-86. doi: 10.1128/jcm.29.11.2578-2586.1991.
7
Chromosomal DNA fingerprint patterns produced with IS6110 as strain-specific markers for epidemiologic study of tuberculosis.以IS6110作为菌株特异性标记产生的染色体DNA指纹图谱用于结核病的流行病学研究。
J Clin Microbiol. 1991 Sep;29(9):2030-3. doi: 10.1128/jcm.29.9.2030-2033.1991.
8
Insertion element IS987 from Mycobacterium bovis BCG is located in a hot-spot integration region for insertion elements in Mycobacterium tuberculosis complex strains.来自卡介苗的插入元件IS987位于结核分枝杆菌复合群菌株中插入元件的热点整合区域。
Infect Immun. 1991 Aug;59(8):2695-705. doi: 10.1128/iai.59.8.2695-2705.1991.
9
An outbreak of tuberculosis with accelerated progression among persons infected with the human immunodeficiency virus. An analysis using restriction-fragment-length polymorphisms.人类免疫缺陷病毒感染者中结核病加速进展的暴发。使用限制性片段长度多态性的分析。
N Engl J Med. 1992 Jan 23;326(4):231-5. doi: 10.1056/NEJM199201233260404.
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An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome.获得性免疫缺陷综合征住院患者中耐多药结核病的暴发。
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对保存的肺组织中结核分枝杆菌北京家族的回顾性分析。

Retrospective analysis of the Beijing family of Mycobacterium tuberculosis in preserved lung tissues.

作者信息

Qian L, Van Embden J D, Van Der Zanden A G, Weltevreden E F, Duanmu H, Douglas J T

机构信息

Department of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA.

出版信息

J Clin Microbiol. 1999 Feb;37(2):471-4. doi: 10.1128/JCM.37.2.471-474.1999.

DOI:10.1128/JCM.37.2.471-474.1999
PMID:9889247
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC84346/
Abstract

Direct repeat spoligotyping of 85 paraffin-embedded lung biopsies was used to investigated the occurrence around Beijing of the Beijing family of Mycobacterium tuberculosis. Samples ranged in time from 1956 to 1990. Hybridization patterns were found with 49 (58%) samples, and 45 (92%) produced typical Beijing family patterns extending over the 34-year period.

摘要

对85份石蜡包埋的肺活检组织进行直接重复间隔寡核苷酸分型，以调查北京地区周围结核分枝杆菌北京家族的出现情况。样本时间跨度从1956年至1990年。在49份（58%）样本中发现了杂交模式，其中45份（92%）产生了典型的北京家族模式，且这种模式在34年期间持续存在。