Qian L, Van Embden J D, Van Der Zanden A G, Weltevreden E F, Duanmu H, Douglas J T
Department of Microbiology, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA.
J Clin Microbiol. 1999 Feb;37(2):471-4. doi: 10.1128/JCM.37.2.471-474.1999.
Direct repeat spoligotyping of 85 paraffin-embedded lung biopsies was used to investigated the occurrence around Beijing of the Beijing family of Mycobacterium tuberculosis. Samples ranged in time from 1956 to 1990. Hybridization patterns were found with 49 (58%) samples, and 45 (92%) produced typical Beijing family patterns extending over the 34-year period.
对85份石蜡包埋的肺活检组织进行直接重复间隔寡核苷酸分型,以调查北京地区周围结核分枝杆菌北京家族的出现情况。样本时间跨度从1956年至1990年。在49份(58%)样本中发现了杂交模式,其中45份(92%)产生了典型的北京家族模式,且这种模式在34年期间持续存在。