Cannizzaro Michael S, Reilly Nicole, Mundt James C, Snyder Peter J
Voice Acoustics Laboratory, WW Clinical Technology (CNS), Pfizer Global Research & Development, Groton Laboratories, Groton, CT 06340, USA.
Clin Linguist Phon. 2005 Dec;19(8):649-58. doi: 10.1080/02699200412331271125.
In this pilot study we sought to determine the reliability and validity of collecting speech and voice acoustical data via telephone transmission for possible future use in large clinical trials. Simultaneous recordings of each participant's speech and voice were made at the point of participation, the local recording (LR), and over a telephone line using a dedicated in-line computerized interactive voice recording system, the remote recording (RR). All voice recordings were made from our laboratory telephone located in Groton, Connecticut to the RR system located in Madison, Wisconsin. All data points were compared on a measure-by-measure basis between the LR and RR recordings. The results suggest that both measures of frequency excursion and of speech motor timing are reliably captured over the telephone. Results are discussed in terms of specific acoustic measures that may be useful and accurately measured via telephone transmission, for examining disease severity and pharmacological intervention for use in a large-scale clinical trial.
在这项试点研究中,我们试图确定通过电话传输收集语音和嗓音声学数据的可靠性和有效性,以便未来可能用于大型临床试验。在参与者参与时进行每位参与者语音和嗓音的同步录音,即本地录音(LR),并使用专用的在线计算机交互式语音记录系统通过电话线进行录音,即远程录音(RR)。所有语音录音均从位于康涅狄格州格罗顿的我们实验室的电话,传输至位于威斯康星州麦迪逊的RR系统。在逐个测量的基础上,对LR和RR录音之间的所有数据点进行比较。结果表明,通过电话能够可靠地获取频率偏移和言语运动时间这两种测量结果。针对可能有用且可通过电话传输准确测量的特定声学测量指标,讨论了相关结果,这些指标可用于检查疾病严重程度以及在大规模临床试验中进行药物干预。