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神经科学临床研究中的脑监测设备：使用传感器、可穿戴设备和移动设备进行远程监测的潜力。

Brain Monitoring Devices in Neuroscience Clinical Research: The Potential of Remote Monitoring Using Sensors, Wearables, and Mobile Devices.

机构信息

ICON Clinical Research, Marlow, UK.

ICON Clinical Research, Dublin, Ireland.

出版信息

Clin Pharmacol Ther. 2018 Jul;104(1):59-71. doi: 10.1002/cpt.1077. Epub 2018 Apr 18.

DOI:10.1002/cpt.1077
PMID:29574776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6032823/
Abstract

The increasing miniaturization and affordability of sensors and circuitry has led to the current level of innovation in the area of wearable and microsensor solutions for health monitoring. This facilitates the development of solutions that can be used to measure complex health outcomes in nonspecialist and remote settings. In this article, we review a number of innovations related to brain monitoring including portable and wearable solutions to directly measure brain electrical activity, and solutions measuring aspects related to brain function such as sleep patterns, gait, cognition, voice acoustics, and gaze analysis. Despite the need for more scientific validation work, we conclude that there is enough understanding of how to implement these approaches as exploratory tools that may provide additional valuable insights due to the rich and frequent data they produce, to justify their inclusion in clinical study protocols.

摘要

传感器和电路的日益小型化和价格降低，推动了可穿戴设备和微传感器在健康监测领域的创新。这使得能够开发出可用于在非专业和远程环境中测量复杂健康结果的解决方案。在本文中，我们回顾了一些与大脑监测相关的创新，包括可直接测量脑电活动的便携式和可穿戴解决方案，以及测量睡眠模式、步态、认知、语音声学和注视分析等与大脑功能相关方面的解决方案。尽管需要进行更多的科学验证工作，但我们的结论是，已经足够了解如何将这些方法作为探索性工具来实施，由于它们产生的丰富而频繁的数据，这些方法可能会提供额外的有价值的见解，因此有理由将其纳入临床研究方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/0d5889a7a430/CPT-104-59-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/4a2a18bbe60e/CPT-104-59-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/0d5889a7a430/CPT-104-59-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/4a2a18bbe60e/CPT-104-59-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/fa35bb82eafa/CPT-104-59-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/0fc2ad1059f4/CPT-104-59-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/97eb6b19a602/CPT-104-59-g004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c83f/6032823/0d5889a7a430/CPT-104-59-g006.jpg

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