Baskett T F, O'Connell C M
Department of Obstetrics and Gynaecology and Perinatal Epidemiology Research Unit, Dalhousie University, Halifax, Nova Scotia, Canada.
J Obstet Gynaecol. 2005 Jan;25(1):7-9. doi: 10.1080/01674820400023408.
Using a provincial perinatal database for 15 years, 1988-2002. Cases were identified with one or more of the following markers of severe maternal morbidity: blood transfusion > or = 5 units, emergency hysterectomy, uterine rupture, eclampsia, intensive care (ICU) admission. There were 159,896 mothers delivered of whom 313 (2.0/1000) had 385 markers of severe morbidity (257 had one, 42 had two, 12 had three, and two had four). The following rates of morbidity were recorded: blood transfusion > or = 5 units 119 (0.74/1000); emergency hysterectomy 88 (0.55/1000); uterine rupture 49 (0.31/1000); eclampsia 46 (0.28/1000); ICU 83 (0.52/1000). There was a statistically significant association between multiparity > or = 1, and emergency hysterectomy and uterine rupture; between age > or = 35 years, and emergency hysterectomy, uterine rupture and ICU; and between caesarean delivery and blood transfusion > or = 5 units, emergency hysterectomy, uterine rupture, eclampsia and ICU. The main contributing obstetric complications were haemorrhage (64.7%) and complications of hypertensive disorders (16.8%).
利用一个省级围产期数据库，时间跨度为1988年至2002年的15年。通过以下一种或多种严重孕产妇发病指标来确定病例：输血≥5单位、急诊子宫切除术、子宫破裂、子痫、入住重症监护病房（ICU）。共有159,896名产妇分娩，其中313名（2.0/1000）有385项严重发病指标（257人有一项，42人有两项，12人有三项，两人有四项）。记录到以下发病率：输血≥5单位119例（0.74/1000）；急诊子宫切除术88例（0.55/1000）；子宫破裂49例（0.31/1000）；子痫46例（0.28/1000）；入住ICU 83例（0.52/1000）。经产妇≥1次与急诊子宫切除术和子宫破裂之间；年龄≥35岁与急诊子宫切除术、子宫破裂和入住ICU之间；以及剖宫产与输血≥5单位、急诊子宫切除术、子宫破裂、子痫和入住ICU之间存在统计学上的显著关联。主要的产科并发症是出血（64.7%）和高血压疾病并发症（16.8%）。
