Murphy Cliona M, Murad Khulood, Deane Richard, Byrne Bridgette, Geary Michael P, McAuliffe Fionnuala M
Rotunda Hospital, Dublin, Ireland.
Eur J Obstet Gynecol Reprod Biol. 2009 Mar;143(1):34-7. doi: 10.1016/j.ejogrb.2008.11.008. Epub 2009 Jan 12.
To assess the prevalence and causes of severe maternal morbidity in Dublin over a two year period from 2004 to 2005.
A prospective cohort study from January 2004 to December 2005 was undertaken in the three large maternity hospitals in Dublin, which serve a population of 1.5 million people. All are tertiary referral centres for obstetrics and neonatology and have an annual combined delivery rate of circa 23,000 births. Cases of severe maternal morbidity were identified. A systems based classification was used. The primary cause of maternal morbidity and the number of events experienced per patient was recorded.
We identified 158 women who fulfilled the definition for severe maternal morbidity, giving a rate of 3.2 per 1000 maternities. There were two maternal deaths during the time period giving mortality to morbidity ratio of 1:79. The commonest cause of severe morbidity was vascular dysfunction related to obstetric haemorrhage. Eclampsia comprised 15.4% of cases. Intensive care or coronary care admission occurred in 12% of cases.
The prevalence of severe maternal morbidity in this population is 3.2/1000 maternities. Obstetric haemorrhage was the main cause of severe maternal morbidity.
评估2004年至2005年这两年间都柏林严重孕产妇发病情况的患病率及病因。
2004年1月至2005年12月在都柏林的三家大型妇产医院进行了一项前瞻性队列研究，这三家医院服务人口达150万。所有医院均为产科和新生儿科的三级转诊中心，年分娩量合计约23000例。确定了严重孕产妇发病病例。采用基于系统的分类方法。记录孕产妇发病的主要原因以及每位患者经历的事件数量。
我们确定了158名符合严重孕产妇发病定义的女性，患病率为每1000例分娩中有3.2例。在此期间有2例孕产妇死亡，死亡率与发病率之比为1:79。严重发病的最常见原因是与产科出血相关的血管功能障碍。子痫占病例的15.4%。12%的病例入住了重症监护病房或冠心病监护病房。
该人群中严重孕产妇发病的患病率为每1000例分娩中有3.2例。产科出血是严重孕产妇发病的主要原因。
