Erkens J A, Janse A F C, Herings R M C
PHARMO Institute, Utrecht, The Netherlands.
Pharmacoepidemiol Drug Saf. 2005 Nov;14(11):821-2. doi: 10.1002/pds.1152.
Since September 2003, cannabis is available for medicinal purposes in Dutch pharmacies to. It was anticipated that the medicinal cannabis use via illegal ways would decrease. The objective of this study was to get insight in the use of medicinal cannabis in daily practise as dispensed by community pharmacies and to characterize the users as well as the symptoms and conditions cannabis is prescribed for.A prospective follow-up study among 200 patients who filled a prescription for medicinal cannabis was performed in the period between September 2003 and January 2004. The patients filled out a structured questionnaire concerning symptoms and conditions and their experience with cannabis. Of all patients, 42% suffered from multiple sclerosis, 11% suffered from rheumatic diseases, and 60% of respondents already used cannabis before the legalization. Cannabis was mainly used for chronic pain and muscle cramp/stiffness.The indication of medicinal cannabis use was in accordance with the labeled indications. However, more than 80% of the patients still obtained cannabis for medicinal purpose from the illegal circuit. Because of the higher prices in pharmacies, ongoing debate on the unproven effectiveness of the drug and the hesitation by physicians to prescribe cannabis.
自2003年9月起,医用大麻在荷兰药店可供使用。预计通过非法途径使用医用大麻的情况会减少。本研究的目的是了解社区药店配发的医用大麻在日常实践中的使用情况,并对使用者以及开具大麻所针对的症状和病症进行特征描述。2003年9月至2004年1月期间,对200名开具了医用大麻处方的患者进行了一项前瞻性随访研究。患者填写了一份关于症状和病症以及他们使用大麻经历的结构化问卷。在所有患者中,42%患有多发性硬化症,11%患有风湿性疾病,60%的受访者在合法化之前就已经使用过大麻。大麻主要用于慢性疼痛和肌肉痉挛/僵硬。医用大麻的使用指征与标签所示指征一致。然而,超过80%的患者仍从非法渠道获取用于医疗目的的大麻。原因在于药店价格更高、关于该药物未经证实的有效性的持续争论以及医生对开具大麻的犹豫态度。