Tunsuriyawong Sutasinee, Puavilai Siripen
Department of Medicine, Ramathibodi Hospital, Mahidol University, Rama VI Rd, Bangkok 10400, Thailand.
J Med Assoc Thai. 2005 May;88(5):678-81.
Herpes zoster was more frequently found in immunocompromised hosts and elderly persons than in general population. The aim of this study is to find out the distributions of skin lesions, treatments, complications of herpes zoster and associated diseases that occur in concomitant with or after herpes zoster infections.
The medical records of the patients diagnosed as herpes zoster between January 1995 - December 2000 were reviewed. Only the patients who were followed up regularly at Ramathibodi hospital for at least 3 years after the first diagnosis of herpes zoster were enrolled into the study. Demographic data, distribution of skin lesions, treatments, complications of herpes zoster and associated diseases were recorded.
Three hundred and ninety-nine cases were enrolled in the study. Three hundred and ninety-eight patients (99.7%) had one dermatomal involvement. Sixty-seven patients (16.8%) had postherpetic neuralgia. Fifty-six patients had associated HIV infection. In 3 years followed up, 17 patients developed HIV infection, 3 patients developed acute leukemia, 2 patients developed mycosis fungoides.
与普通人群相比，免疫功能低下者和老年人中带状疱疹更为常见。本研究的目的是找出带状疱疹皮肤损害的分布情况、治疗方法、并发症以及带状疱疹感染期间或之后出现的相关疾病。
回顾了1995年1月至2000年12月期间诊断为带状疱疹的患者的病历。仅纳入在拉玛蒂博迪医院首次诊断为带状疱疹后至少定期随访3年的患者。记录人口统计学数据、皮肤损害分布、治疗方法、带状疱疹并发症及相关疾病。
399例患者纳入本研究。398例患者（99.7%）有一个皮节受累。67例患者（16.8%）发生带状疱疹后神经痛。56例患者合并HIV感染。在3年的随访中，17例患者发生HIV感染，3例患者发生急性白血病，2例患者发生蕈样肉芽肿。
