Banaś Anna, Lass Piotr, Straniewska Dorota
Klinika Chorób Psychicznych i Zaburzeń Nerwicowych AMG, Gdansk.
Psychiatr Pol. 2005 May-Jun;39(3):497-507.
The aim of the study was to estimate usefulness of the single photon emission computed tomography (SPECT) for the diagnostics of the depressive disorders, neurotic and eating disorders, and detect the organic factors and correlation between cerebral hypoperfusion and results of Benton's and Bender's tests.
Study of 43 patients (33 women and 10 men) aged 16--59 years (SD+38, 65 +/- 11, 62) which were examined with single photon emission computed tomography (SPECT) and Benton's and Bender's tests during their treatment in the 1st Department of Psychiatry, Medical University in Gdańsk in the years 2000 to 2003. 30 patients were diagnosed with depression (first depressive episodes--8, recurrent depressive disorders--9, organic depression--13), 8--neurotic disorders and 5--eating disorders.
SPECT in 38 (88,37%) cases showed hypoperfusion mostly on the left side and in the frontal region. Hypoperfusion in the recurrent depressive disorders was considerably greater (nearly significant) in comparison with the first depressive episodes. The correlation between hypoperfusion and CNS impairment examined with Benton's and Bender's tests was observed. The correlation coefficient of was 0.6845.
本研究旨在评估单光子发射计算机断层扫描（SPECT）在诊断抑郁症、神经症和饮食失调方面的效用，并检测器质性因素以及脑灌注不足与本顿氏和本德氏测试结果之间的相关性。
对43例年龄在16至59岁（标准差 + 38，65 ± 11，62）的患者（33名女性和10名男性）进行研究，这些患者于2000年至2003年在格但斯克医科大学第一精神科接受治疗期间接受了单光子发射计算机断层扫描（SPECT）以及本顿氏和本德氏测试。30例患者被诊断为抑郁症（首次抑郁发作——8例，复发性抑郁症——9例，器质性抑郁症——13例），8例为神经症，5例为饮食失调。
SPECT在38例（88.37%）病例中显示灌注不足，主要发生在左侧和额叶区域。与首次抑郁发作相比，复发性抑郁症中的灌注不足程度明显更大（接近显著）。观察到灌注不足与通过本顿氏和本德氏测试检查的中枢神经系统损伤之间存在相关性。相关系数为0.6845。
