Mok C C
Department of Medicine and Geriatrics, Tuen Mun Hospital, New Territories, Hong Kong, China.
Best Pract Res Clin Rheumatol. 2005 Oct;19(5):741-66. doi: 10.1016/j.berh.2005.04.002.
Gastrointestinal (GI) manifestations of systemic lupus erythematosus (SLE) are protean. Any part of the GI tract and the hepatobiliary system can be involved. Up to two-third of SLE patients develop GI symptoms at some stage of their illnesses. Clinical presentations of GI lupus are non-specific and can be difficult to differentiate from infective, thrombotic, therapy-related and non-SLE etiologies. Clinical acumen and appropriate endoscopic, biopsy and imaging procedures are essential for establishing the correct diagnosis. Acute abdominal pain in SLE patients can herald an intra-abdominal catastrophe and should be evaluated promptly. Surgical intervention should be instituted without delay if conservative management fails or when there is clinical or radiological suspicion of visceral perforation or intra-abdominal collections.
系统性红斑狼疮（SLE）的胃肠道（GI）表现多种多样。胃肠道和肝胆系统的任何部位都可能受累。多达三分之二的SLE患者在疾病的某个阶段会出现胃肠道症状。胃肠道狼疮的临床表现不具有特异性，可能难以与感染性、血栓性、治疗相关及非SLE病因相鉴别。临床敏锐度以及适当的内镜检查、活检和影像学检查程序对于确立正确诊断至关重要。SLE患者出现急性腹痛可能预示着腹腔内的严重病变，应立即进行评估。如果保守治疗失败，或者临床或影像学怀疑有内脏穿孔或腹腔内积液，应立即进行手术干预。
