Schutz R, Delclaux C, Balloul-Delclaux E, Pignol J P
Service de Réanimation polyvalente, Hôpital de Bobo Dioulasso, Burkina Faso.
Rev Mal Respir. 1992;9(3):313-7.
Thirty five patients, twenty nine men and six women with a mean age of twenty six and suffering from a pyothorax 23% or a pyopneumothorax 77% of whom 41% had a bronchopleural fistula on chronic evolution (greater than one month before drainage), had been treated using drainage and lavage with iodised polyvinylpyrrolidine without local or general antibiotics. This treatment enabled thirty four patients to be cured with some moderate radiological sequelae, a 50% restitution "ad integrum". The importance of the sequelae was correlated with increased aged (P less than 0.001), a delay before drainage (P less than 0.001) and a prolonged duration of drainage (P less than 0.01), to multiple organisms (P less than 0.01) and the presence of a pneumothorax (P less than 0.02) and to a tuberculous origin of the effusion (P less than 0.01). These two latter factors were the cause of a prolongation of the duration of drainage (P less than 0.01). Tuberculous patients who on average were older (P less than 0.05) and had a prolonged period of drainage (P less than 0.01) presented with major immediate radiological sequelae (P less than 0.01). In conclusion the technique of drainage using iodised polyvinylpyrrolidine gave excellent results in cases of non-tuberculous pyothorax in young subjects, but gave less impressive results in subjects suffering from tuberculosis, because of the significant radiological sequelae.
35例患者,其中29例男性,6例女性,平均年龄26岁,患有脓胸(23%)或脓气胸(77%),其中41%在慢性病程(引流前超过1个月)时有支气管胸膜瘘,采用含碘聚乙烯吡咯烷酮进行引流和灌洗治疗,未使用局部或全身抗生素。该治疗使34例患者治愈,遗留一些中度放射学后遗症,50%恢复正常。后遗症的严重程度与年龄增加(P<0.001)、引流前延迟(P<0.001)、引流持续时间延长(P<0.01)、多种病原体感染(P<0.01)、气胸的存在(P<0.02)以及胸腔积液的结核起源(P<0.01)相关。后两个因素导致引流持续时间延长(P<0.01)。结核患者平均年龄较大(P<0.05)且引流时间延长(P<0.01),出现严重的即刻放射学后遗症(P<0.01)。总之,含碘聚乙烯吡咯烷酮引流技术在年轻非结核性脓胸病例中效果极佳,但在结核患者中效果较差,因为会出现明显的放射学后遗症。