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MAGE-1/Heat shock protein 70/MAGE-3 fusion protein vaccine in nanoemulsion enhances cellular and humoral immune responses to MAGE-1 or MAGE-3 in vivo.

作者信息

Ge Wei, Sui Yan-Fang, Wu Dao-Cheng, Sun Yu-Jing, Chen Guang-Sheng, Li Zeng-Shan, Si Shao-Yan, Hu Pei-Zhen, Huang Yang, Zhang Xiu-Min

机构信息

State Key Laboratory of Cancer Biology, Department of Pathology, Xi Jing Hospital, Fourth Military Medical University, Xi'an, 710032 Shaanxi Province, China.

出版信息

Cancer Immunol Immunother. 2006 Jul;55(7):841-9. doi: 10.1007/s00262-005-0073-y. Epub 2005 Sep 6.

DOI:10.1007/s00262-005-0073-y
PMID:16155756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11030595/
Abstract
摘要

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1
MAGE-1/Heat shock protein 70/MAGE-3 fusion protein vaccine in nanoemulsion enhances cellular and humoral immune responses to MAGE-1 or MAGE-3 in vivo.纳米乳剂中的MAGE-1/热休克蛋白70/MAGE-3融合蛋白疫苗可增强体内对MAGE-1或MAGE-3的细胞免疫和体液免疫反应。
Cancer Immunol Immunother. 2006 Jul;55(7):841-9. doi: 10.1007/s00262-005-0073-y. Epub 2005 Sep 6.
2
The antitumor immune responses induced by nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine following peroral administration route.经口服给药途径后,纳米乳剂包封的MAGE1-HSP70/SEA复合蛋白疫苗诱导的抗肿瘤免疫反应。
Cancer Immunol Immunother. 2009 Feb;58(2):201-8. doi: 10.1007/s00262-008-0539-9. Epub 2008 Jun 4.
3
A novel DNA vaccine constructed by heat shock protein 70 and melanoma antigen-encoding gene 3 against tumorigenesis.一种由热休克蛋白70和黑色素瘤抗原编码基因3构建的新型DNA疫苗用于抗肿瘤发生。
Indian J Exp Biol. 2010 May;48(5):436-43.
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Heat shock protein 70/MAGE-3 fusion protein vaccine can enhance cellular and humoral immune responses to MAGE-3 in vivo.热休克蛋白70/MAGE-3融合蛋白疫苗可在体内增强对MAGE-3的细胞免疫和体液免疫反应。
Cancer Immunol Immunother. 2005 Sep;54(9):907-14. doi: 10.1007/s00262-004-0660-3. Epub 2005 Mar 9.
5
The antitumor immune responses induced by nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine following different administration routes.纳米乳剂包裹的MAGE1-HSP70/SEA复合蛋白疫苗经不同给药途径诱导的抗肿瘤免疫反应。
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Fusion of Hsp70 to Mage-a1 enhances the potency of vaccine-specific immune responses.热休克蛋白70(Hsp70)与黑色素瘤抗原基因-a1(Mage-a1)融合可增强疫苗特异性免疫反应的效力。
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Heat shock protein 70 fused to or complexed with hantavirus nucleocapsid protein significantly enhances specific humoral and cellular immune responses in C57BL/6 mice.与汉坦病毒核衣壳蛋白融合或复合的热休克蛋白70可显著增强C57BL/6小鼠的特异性体液免疫和细胞免疫反应。
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Nanoparticle drug delivery systems: an excellent carrier for tumor peptide vaccines.纳米颗粒药物递送系统:肿瘤肽疫苗的优秀载体。
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Gas‑filled ultrasound microbubbles enhance the immunoactivity of the HSP70‑MAGEA1 fusion protein against MAGEA1‑expressing tumours.充气体超声微泡增强 HSP70-MAGEA1 融合蛋白对表达 MAGEA1 肿瘤的免疫活性。
Mol Med Rep. 2018 Jul;18(1):315-321. doi: 10.3892/mmr.2018.9003. Epub 2018 May 9.
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Nanomaterials in the application of tumor vaccines: advantages and disadvantages.纳米材料在肿瘤疫苗中的应用:优缺点。
Onco Targets Ther. 2013 Jun 5;6:629-34. doi: 10.2147/OTT.S41902. Print 2013.
4
Nanoparticle delivery systems in cancer vaccines.癌症疫苗中的纳米颗粒递送系统。
Pharm Res. 2011 Feb;28(2):215-36. doi: 10.1007/s11095-010-0241-4. Epub 2010 Aug 19.
5
The antitumor immune responses induced by nanoemulsion-encapsulated MAGE1-HSP70/SEA complex protein vaccine following peroral administration route.经口服给药途径后,纳米乳剂包封的MAGE1-HSP70/SEA复合蛋白疫苗诱导的抗肿瘤免疫反应。
Cancer Immunol Immunother. 2009 Feb;58(2):201-8. doi: 10.1007/s00262-008-0539-9. Epub 2008 Jun 4.
6
Lipid-based colloidal carriers for peptide and protein delivery--liposomes versus lipid nanoparticles.用于肽和蛋白质递送的脂质基胶体载体——脂质体与脂质纳米颗粒
Int J Nanomedicine. 2007;2(4):595-607.

本文引用的文献

1
Heat shock protein 70/MAGE-3 fusion protein vaccine can enhance cellular and humoral immune responses to MAGE-3 in vivo.热休克蛋白70/MAGE-3融合蛋白疫苗可在体内增强对MAGE-3的细胞免疫和体液免疫反应。
Cancer Immunol Immunother. 2005 Sep;54(9):907-14. doi: 10.1007/s00262-004-0660-3. Epub 2005 Mar 9.
2
[Preparation and characterization of nanoemulsion].
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2005 Jan;21(1):69-71, 75.
3
Heat shock protein 70 / MAGE-1 tumor vaccine can enhance the potency of MAGE-1-specific cellular immune responses in vivo.热休克蛋白70/MAGE-1肿瘤疫苗可增强体内MAGE-1特异性细胞免疫反应的效力。
Cancer Immunol Immunother. 2004 Sep;53(9):825-34. doi: 10.1007/s00262-004-0536-6. Epub 2004 Apr 30.
4
Development of immune response that protects mice from viral pneumonitis after a single intranasal immunization with influenza A virus and nanoemulsion.用甲型流感病毒和纳米乳剂单次鼻内免疫后,保护小鼠免受病毒性肺炎的免疫反应的发展。
Vaccine. 2003 Sep 8;21(25-26):3801-14. doi: 10.1016/s0264-410x(03)00381-5.
5
In vitro gene transfection in human glioma cells using a novel and less cytotoxic artificial lipoprotein delivery system.使用新型且细胞毒性较小的人工脂蛋白递送系统对人胶质瘤细胞进行体外基因转染。
Pharm Res. 2003 May;20(5):738-44. doi: 10.1023/a:1023477317668.
6
Gene therapy progress and prospects: nonviral vectors.基因治疗的进展与前景:非病毒载体
Gene Ther. 2002 Dec;9(24):1647-52. doi: 10.1038/sj.gt.3301923.
7
Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells.用于药物递送的纳米阳离子水凝胶:制备、性质及其与细胞的相互作用
Adv Drug Deliv Rev. 2002 Jan 17;54(1):135-47. doi: 10.1016/s0169-409x(01)00245-9.
8
Topical transfection using plasmid DNA in a water-in-oil nanoemulsion.
Int J Pharm. 2001 Jun 19;221(1-2):23-34. doi: 10.1016/s0378-5173(01)00672-x.
9
Long-circulating and target-specific nanoparticles: theory to practice.长循环且靶向特异性纳米颗粒:从理论到实践
Pharmacol Rev. 2001 Jun;53(2):283-318.
10
Adjuvants designed for veterinary and human vaccines.专为兽用和人用疫苗设计的佐剂。
Vaccine. 2001 Mar 21;19(17-19):2666-72. doi: 10.1016/s0264-410x(00)00498-9.