Kreitzman S N, Coxon A Y, Johnson P G, Ryde S J
Howard Foundation Research, BSIA Ltd, University College of Swansea, UK.
Am J Clin Nutr. 1992 Jul;56(1 Suppl):258S-261S. doi: 10.1093/ajcn/56.1.258S.
The assumption that total energy expended is related to resting metabolic rate (RMR) has not been validated. Intuitively, weight lost should be determined by the difference between the total energy consumed and the total energy expended. The ratio of actual daily energy usage to RMR by subjects dieting for 11 wk on a 1695-kJ (405-kcal) very-low-calorie diet (VLCD) was variable 1.9 +/- 0.3 (range 1.47-2.36). Weight loss correlated with total energy expenditure measured by 2H2 18O and not RMR, body mass index or body composition. Although RMR may be a reliable indicator of fat-free mass, there is little evidence that subjects with similar RMR will lose comparable weight or have comparable difficulty in weight maintenance.
总能量消耗与静息代谢率（RMR）相关这一假设尚未得到验证。直观地说，体重减轻应由总能量消耗与总能量摄入之间的差值决定。在1695千焦（405千卡）极低热量饮食（VLCD）下节食11周的受试者，其实际每日能量消耗与RMR的比值变化范围为1.9±0.3（1.47 - 2.36）。体重减轻与通过2H2 18O测量的总能量消耗相关，而非与RMR、体重指数或身体成分相关。尽管RMR可能是去脂体重的可靠指标，但几乎没有证据表明具有相似RMR的受试者会减轻相当的体重或在维持体重方面有相当的难度。
