Stuart D, Orelowitz J, Bank S, Stark B, Hilton E
Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, New York.
Am J Gastroenterol. 1992 Jul;87(7):883-5.
We report a patient with disseminated cholangiocarcinoma who developed systemic fungemia subsequent to endoscopic retrograde cholangiopancreatography (ERCP) and stent replacement. Despite intensive systemic antifungal therapy with iv amphotericin B, the patient developed multiple complications and eventually succumbed to her underlying disease. Cultures of the removed stent and blood were positive for the same organism, Torulopsis glabrata. In an immunocompromised host during ERCP manipulation, fungal pathogens should be considered in post-stent septicemia.
我们报告了一例播散性胆管癌患者,该患者在接受内镜逆行胰胆管造影术(ERCP)及支架置换术后发生了全身性真菌血症。尽管使用静脉注射两性霉素B进行了强化的全身抗真菌治疗,但患者仍出现了多种并发症,最终死于基础疾病。取出的支架和血液培养结果显示为同一病原体——光滑念珠菌呈阳性。对于免疫功能低下的宿主,在进行ERCP操作时,支架置入后发生败血症应考虑真菌病原体感染。