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免疫功能正常患者经内镜逆行胰胆管造影术后念珠菌血症:一例病例报告及文献综述

Candidemia after endoscopic retrograde cholangiopancreatography in an immunocompetent patient: A case report and literature review.

作者信息

Park Tae Young, Yang Young Joo, Shin Suk Pyo, Bang Chang Seok, Suk Ki Tae, Baik Gwang Ho, Kim Dong Joon

机构信息

Department of Internal Medicine, Inje University Seoul Paik Hospital, Seoul, Korea.

Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.

出版信息

Saudi J Gastroenterol. 2018 Mar-Apr;24(2):135-137. doi: 10.4103/sjg.SJG_536_17.

Abstract

Candidemia is a rare adverse event of endoscopic retrograde cholangiopancreatography (ERCP). To date, several case reports of post-ERCP candidemia have been reported. Recently, we experienced a case of disseminated candidemia caused by Candida albicans with secondary complications of acute respiratory distress syndrome, acute kidney injury, and hematogenous candidal endophthalmitis following ERCP in a young healthy patient without well-recognized risk factors for candidemia. After intravenous and intravitreal antifungal therapy and intensive care, the candidemia resolved, and the patient was discharged without further sequela. The present case alerted us to consider candidemia as a rare but potentially fatal adverse event of ERCP, even in an immunocompetent host.

摘要

念珠菌血症是内镜逆行胰胆管造影术(ERCP)的一种罕见不良事件。迄今为止,已有数篇关于ERCP术后念珠菌血症的病例报告。最近,我们遇到一例由白色念珠菌引起的播散性念珠菌血症,该年轻健康患者在进行ERCP后出现急性呼吸窘迫综合征、急性肾损伤和血源性念珠菌性眼内炎等继发并发症,且无公认的念珠菌血症危险因素。经过静脉和玻璃体内抗真菌治疗及重症监护,念珠菌血症得到缓解,患者出院时无进一步后遗症。本病例提醒我们,即使在免疫功能正常的宿主中,也应将念珠菌血症视为ERCP罕见但可能致命的不良事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285c/5900474/388eef023620/SJG-24-135-g001.jpg

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