Sadick Maliha, Sadick Haneen, Hörmann Karl, Düber Christoph, Diehl Steffen J
Institute of Clinical Radiology, University Hospital Mannheim, Germany.
Onkologie. 2005 Oct;28(10):477-81. doi: 10.1159/000087127. Epub 2005 Sep 9.
Head and neck cancer accounts for 5% of all malignancies worldwide. The presence of lymph node metastases and vascular infiltration influence patient outcome. This prospective study describes the preoperative morphologic assessment of the vascular status of patients with head and neck tumors by means of high spatial resolution and extended coverage of the arterial and venous system reaching from the supra-aortic region to the skull base.
Cross-sectional imaging combined with contrast-enhanced 3D-maximum intensity projection MR angiography (3D-MRA) was applied using a dedicated head and neck coil with a 4-channel panorama array system interface to assess vascular involvement in patients with suspected head and neck cancer. 32 patients underwent preoperative assessment by magnetic resonance imaging (MRI). The results were then correlated with surgical and histological findings.
3 of the 32 patients (9%) demonstrated involvement of the arterial system. In 2 of these 3 cases, MRA correctly predicted the arterial status, while in 1 case it gave a false negative result. 11 of the 32 patients (34%) presented with involvement of the venous system. 10 cases showed complete concordance between the findings of the MR venography and the intraoperative status, while in 1 case a false negative result was produced.
In patients with suspected head and neck tumors, 3D-MRA in combination with cross sectional imaging is a valuable diagnostic tool for the detection of vascular involvement.
头颈癌占全球所有恶性肿瘤的5%。淋巴结转移和血管浸润的存在会影响患者的预后。这项前瞻性研究描述了通过高空间分辨率和从主动脉弓上区域到颅底的动静脉系统的扩展覆盖，对头颈肿瘤患者血管状态进行术前形态学评估。
采用具有4通道全景阵列系统接口的专用头颈线圈，应用横断面成像结合对比增强三维最大强度投影磁共振血管造影（3D-MRA）来评估疑似头颈癌患者的血管受累情况。32例患者接受了术前磁共振成像（MRI）评估。然后将结果与手术和组织学结果进行对比。
32例患者中有3例（9%）显示动脉系统受累。在这3例中的2例中，MRA正确预测了动脉状态，而在1例中给出了假阴性结果。32例患者中有11例（34%）出现静脉系统受累。10例患者的磁共振静脉造影结果与术中情况完全一致，而在1例中产生了假阴性结果。
对于疑似头颈肿瘤的患者，3D-MRA结合横断面成像对于检测血管受累是一种有价值的诊断工具。
