西里亚乔治诺卡菌是日本和泰国诺卡菌病的重要病原体。
Nocardia cyriacigeorgica is a significant pathogen responsible for nocardiosis in Japan and Thailand.
作者信息
Kageyama Akiko, Hoshino Yasutaka, Yazawa Katsukiyo, Poonwan Natteewan, Takeshita Nobuyoshi, Maki Satoshi, Mikami Yuzuru
机构信息
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8673, Japan.
出版信息
Mycopathologia. 2005 Aug;160(1):15-9. doi: 10.1007/s11046-005-3050-2.
Nocardia cyriacigeorgica is a recently described species. During routine diagnostic testing of 121 clinical isolates, we found that about one fourth of the strains from Japan (19 isolates) and Thailand (8 isolates), which were identified in our laboratories as N. asteroides, in fact belong to N. cyriacigeorgica. To our knowledge, this is the first report of infection due to N. cyriacigeorgica in Japan and Thailand, and the third report of infection anywhere in the world. Although N. cyriacigeorgica is usually differentiated from other Nocardia species by utilization of glucose and gluconate, we found that it can also be differentiated by a characteristic synergistic effect between imipenem (IPM) and tobramycin (TOB).
西里亚乔治诺卡菌是一种最近才被描述的菌种。在对121株临床分离株进行常规诊断检测期间，我们发现，在我们实验室被鉴定为星状诺卡菌的来自日本的约四分之一菌株（19株）和来自泰国的菌株（8株），实际上属于西里亚乔治诺卡菌。据我们所知，这是日本和泰国关于西里亚乔治诺卡菌感染的首次报告，也是世界上任何地方关于该菌感染的第三次报告。尽管西里亚乔治诺卡菌通常通过利用葡萄糖和葡萄糖酸盐与其他诺卡菌属菌种相鉴别，但我们发现它也可通过亚胺培南（IPM）和妥布霉素（TOB）之间的一种特征性协同效应来鉴别。
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