Stuhlbacher A, Maltby L
Department of Animal and Plant Sciences, University of Sheffield, United Kingdom.
Arch Environ Contam Toxicol. 1992 Apr;22(3):319-24. doi: 10.1007/BF00212093.
The ability of Gammarus pulex to develop cadmium resistance through physiological acclimation was investigated. Organisms were found to be significantly more tolerant to acute cadmium toxicity after pre-exposure to sublethal concentrations of cadmium and zinc. The induced elevation in cadmium tolerance was shown to be associated with an increase in the body concentration of a metallothionein-like protein. Pre-exposure had no apparent effect on cadmium uptake, although it did influence the distribution of cadmium within the organisms. Whereas pre-exposure to low levels of zinc and cadmium increased cadmium tolerances in acute tests, it had no observable effects on sublethal responses measured during chronic exposure.
研究了蚤状溞通过生理适应产生镉抗性的能力。发现生物体在预先暴露于亚致死浓度的镉和锌后，对急性镉毒性的耐受性显著提高。镉耐受性的诱导升高与一种类金属硫蛋白的体内浓度增加有关。预先暴露对镉的吸收没有明显影响，尽管它确实影响了镉在生物体内的分布。虽然在急性试验中预先暴露于低水平的锌和镉可提高镉耐受性，但对慢性暴露期间测量的亚致死反应没有可观察到的影响。
