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慢性淋巴细胞白血病单克隆抗体治疗的最新进展

Update on monoclonal antibody therapy in chronic lymphocytic leukemia.

作者信息

Zent Clive S, Kay Neil E

机构信息

Division of Hematology, Mayo Clinic, Rochester, MN 55905, USA.

出版信息

Clin Adv Hematol Oncol. 2004 Feb;2(2):107-13.

PMID:16163170
Abstract

Monoclonal antibodies are an evolving treatment modality in chronic lymphocytic leukemia that has the potential to provide more effective and safer targeted therapy. This review provides historical context and detailed analysis of current developments, as well as an outline for future prospects and expectations in this exciting new arena of therapeutics.

摘要

单克隆抗体是慢性淋巴细胞白血病中一种不断发展的治疗方式,有潜力提供更有效、更安全的靶向治疗。本文献综述提供了历史背景以及对当前进展的详细分析,还概述了这一令人兴奋的新治疗领域的未来前景与期望。

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Update on monoclonal antibody therapy in chronic lymphocytic leukemia.慢性淋巴细胞白血病单克隆抗体治疗的最新进展
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Alemtuzumab (Campath-1H) in the treatment of chronic lymphocytic leukemia.阿仑单抗(Campath-1H)治疗慢性淋巴细胞白血病
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Charting the path to the cure of chronic lymphocytic leukemia: consolidation strategies currently lead the way.探寻慢性淋巴细胞白血病的治愈之路:巩固策略引领前行。
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Effect of alemtuzumab on neoplastic B cells.阿仑单抗对肿瘤性B细胞的作用。
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引用本文的文献

1
Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer.确定阿仑单抗作为一种抗髓样细胞抗血管生成疗法用于治疗卵巢癌。
J Transl Med. 2009 Jun 19;7:49. doi: 10.1186/1479-5876-7-49.
2
Phase I study of a novel pro-apoptotic drug R-etodolac in patients with B-cell chronic lymphocytic leukemia.新型促凋亡药物R-依托度酸治疗B细胞慢性淋巴细胞白血病患者的I期研究
Invest New Drugs. 2008 Apr;26(2):139-49. doi: 10.1007/s10637-007-9106-z. Epub 2007 Dec 20.