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阿尔茨海默病患者家庭照料者的焦虑与抑郁:LASER-AD研究

Anxiety and depression in family caregivers of people with Alzheimer disease: the LASER-AD study.

作者信息

Mahoney Rachel, Regan Ciaran, Katona Cornelius, Livingston Gill

机构信息

Dept. of Mental Health Sciences, University College London, Holborn Union Building, Archway Campus, Highgate Hill, London N19 5LW, UK.

出版信息

Am J Geriatr Psychiatry. 2005 Sep;13(9):795-801. doi: 10.1176/appi.ajgp.13.9.795.

Abstract

OBJECTIVE

There are high rates of stress, distress, and psychological illness in family caregivers of people with dementia. Female caregivers and those caring for people with neuropsychiatric symptoms are particularly at risk. The authors report on the prevalence of anxiety and depression in a sample of family caregivers of people with Alzheimer disease (AD) and compare the characteristics of those who did or did not have those conditions.

METHODS

A group of 153 people with AD and their caregivers were interviewed as part of a larger study of AD.

RESULTS

In all, 23.5% of caregivers scored at or above caseness level for anxiety, and 10.5%, at levels for depression. Care-recipient (CR) activities of daily living (ADL) impairment, being a caregiver living with the CR, being a female caregiver, reporting a poorer quality of relationship with the CR, and caregivers reporting their health as being poor all predicted anxiety disorder. CR irritability, caregivers reporting poor health, and a poorer quality of relationship with the CR predicted depression.

CONCLUSIONS

Clinicians should be aware of the high rates of anxiety as well as depressive symptoms in family caregivers of people with AD, especially in female caregivers. CRs and Caregivers' impaired physical health put them at risk for psychological morbidity and should be treated energetically. A poor-quality relationship between the caregiver and the CR predicts both caregiver depression and anxiety. Caregivers living with the CR are much more likely to be anxious than depressed.

摘要

目的

痴呆症患者的家庭照护者中,压力、痛苦和心理疾病的发生率很高。女性照护者以及那些照护有神经精神症状患者的人风险尤其高。作者报告了阿尔茨海默病(AD)患者家庭照护者样本中焦虑和抑郁的患病率,并比较了有或没有这些情况的照护者的特征。

方法

作为一项关于AD的更大规模研究的一部分,对153名AD患者及其照护者进行了访谈。

结果

总体而言,23.5%的照护者焦虑得分达到或高于病例水平,10.5%的照护者抑郁得分达到病例水平。受照护者(CR)的日常生活活动(ADL)受损、与CR同住的照护者、女性照护者、报告与CR的关系质量较差以及照护者报告自己健康状况不佳,均预示着焦虑症。CR易怒、照护者报告健康状况不佳以及与CR的关系质量较差预示着抑郁症。

结论

临床医生应意识到AD患者家庭照护者中焦虑和抑郁症状的高发生率,尤其是女性照护者。CR和照护者的身体健康受损使他们面临心理发病的风险,应积极治疗。照护者与CR之间的低质量关系预示着照护者的抑郁和焦虑。与CR同住的照护者焦虑的可能性比抑郁大得多。

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