Tabuchi Keiji, Nomura Masatake, Murashita Hidekazu, Fujisawa Yasuhiro, Tsuji Shigeki, Okubo Hideki, Hara Akira
Department of Otolaryngology, Doctorial Program in Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Auris Nasus Larynx. 2006 Jun;33(2):231-3. doi: 10.1016/j.anl.2005.07.008. Epub 2005 Sep 15.
Pemphigus vulgaris and bullous pemphigoid are autoimmune blistering diseases of the skin and the mucosa characterized by circulating autoantibodies. Coexistence of these lesions is extremely uncommon. We report herein a case of both pemphigus vulgaris and bullous pemphigoid which occurred in the upper aerodigestive tract. The diagnosis was made based on the circulating autoantibodies and direct immunofluorescent studies. The literature on this subject is reviewed.
寻常型天疱疮和大疱性类天疱疮是皮肤和黏膜的自身免疫性水疱病，其特征为循环自身抗体。这些皮损同时存在极为罕见。我们在此报告1例发生于上消化道的寻常型天疱疮和大疱性类天疱疮病例。诊断基于循环自身抗体及直接免疫荧光研究。并对该主题的文献进行了综述。
