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乳腺癌生存中的种族与社会经济地位

Race and socio-economic status in survival from breast cancer.

作者信息

Dayal H H, Power R N, Chiu C

出版信息

J Chronic Dis. 1982;35(8):675-83. doi: 10.1016/0021-9681(82)90020-0.

Abstract

The survival data on 515 white and 388 black female breast cancer patients seen at the Medial College of Virginia between 1968 and 1977 were analyzed to study the effect of age, stage and race on survival prognosis. For a subset of the data representing patients from the city of Richmond (117 white and 206 black), socio-economic status (SES) information was generated on the basis of six predictors of SES and, in addition, the role of social class was studied. Each of these factors has a significant association with survival time. In particular, the probability of surviving a given length of time after diagnosis is ordered according to the socio-economic level and the statistical test for dose response show a highly significant directional relationship. Age and stage do not explain the difference in survival between the two races. Race and SES are highly associated; a higher proportion of blacks than whites come from the lower end of the socio-economic scale. Moreover, the racial difference in survival becomes insignificant when it is adjusted for the distribution of socio-economic levels. This suggests that the observed difference in breast cancer survival between blacks and whites is, to a large extent, due to the difference between the two races with respect to the distribution of socio-economic status.

摘要

对1968年至1977年间在弗吉尼亚医学院就诊的515名白人女性和388名黑人女性乳腺癌患者的生存数据进行了分析,以研究年龄、分期和种族对生存预后的影响。对于代表里士满市患者的数据子集(117名白人患者和206名黑人患者),根据社会经济地位(SES)的六个预测因素生成了社会经济地位信息,此外,还研究了社会阶层的作用。这些因素中的每一个都与生存时间有显著关联。特别是,根据社会经济水平对诊断后存活特定时长的概率进行排序,剂量反应的统计检验显示出高度显著的方向性关联。年龄和分期并不能解释两个种族之间的生存差异。种族与社会经济地位高度相关;来自社会经济底层的黑人比例高于白人。此外,在根据社会经济水平分布进行调整后,生存方面的种族差异变得不显著。这表明,观察到的黑人和白人乳腺癌患者生存差异在很大程度上是由于两个种族在社会经济地位分布方面的差异。

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