Drewel Brian T, Giraud David W, Davy Sarah R, Driskell Judy A
Department of Nutrition and Health Sciences, University of Nebraska, Lincoln, NE 68583-0806, USA.
J Nutr Biochem. 2006 Feb;17(2):132-8. doi: 10.1016/j.jnutbio.2005.06.003. Epub 2005 Jul 28.
In that data were not available on the vitamin E status of young children, the aim of the study was to evaluate the vitamin E status of preschool children by three commonly used criteria: vitamin E intakes, plasma alpha-tocopherol concentrations and plasma alpha-tocopherol/total lipid ratios. Twenty-two ethnically diverse preschool children (13 males and 9 females), aged 2 to 5 years, living in Lincoln, NE, served as subjects. The subjects were in two groups: 2-3 and 4-5 years old. Energy, fat, and alpha- and gamma-tocopherol intakes of the subjects were estimated utilizing two 24-h food recalls. Plasma alpha- and gamma-tocopherol and total lipid concentrations were ascertained. No significant differences by age grouping or gender were observed for vitamin E intakes, plasma alpha-tocopherol concentrations, plasma gamma-tocopherol concentrations and plasma alpha-tocopherol/total lipid ratios of subjects. Plasma alpha-tocopherol concentrations indicative of less than adequate status (<12 micromol/L) were observed in 91% of the children, and values <7 micromol/L (proposed cutoff for pediatric populations) in 68%. Sixty-eight percent of the subjects had plasma alpha-tocopherol/total lipid values <0.8 mg/g. The majority of the 2- to 5-year-old children included in the study had less than adequate vitamin E status.
由于没有关于幼儿维生素E状况的数据，本研究的目的是通过三种常用标准评估学龄前儿童的维生素E状况：维生素E摄入量、血浆α-生育酚浓度和血浆α-生育酚/总脂质比率。居住在内布拉斯加州林肯市的22名2至5岁、种族各异的学龄前儿童（13名男性和9名女性）作为研究对象。研究对象分为两组：2 - 3岁组和4 - 5岁组。利用两次24小时饮食回顾法估算研究对象的能量、脂肪以及α-和γ-生育酚摄入量。测定血浆α-和γ-生育酚以及总脂质浓度。研究对象的维生素E摄入量、血浆α-生育酚浓度、血浆γ-生育酚浓度和血浆α-生育酚/总脂质比率在年龄分组或性别方面均未观察到显著差异。91%的儿童血浆α-生育酚浓度表明其状况不足（<12微摩尔/升），68%的儿童血浆α-生育酚浓度<7微摩尔/升（儿科人群建议的临界值）。68%的研究对象血浆α-生育酚/总脂质值<0.8毫克/克。本研究纳入的大多数2至5岁儿童维生素E状况不足。
