Nin Tomomi, Sakagami Masafumi, Sone-Okunaka Mieko, Muto Toshihiko, Mishiro Yasuo, Fukazawa Keijiro
Department of Otolaryngology, Hyogo College of Medicine, Mukogawa, Nishinomiya City, Hyogo 663-8501, Japan.
Auris Nasus Larynx. 2006 Mar;33(1):13-7. doi: 10.1016/j.anl.2005.07.015. Epub 2005 Sep 19.
To investigate prospectively the clinical manifestations and the functional recovery of taste after section of chorda tympani nerve (CTN) during middle ear surgery, the subjective and objective study on the patients was performed.
Thirty-five patients underwent surgery with unilateral (n=32) or bilateral (n=3) section of CTN between January 2000 and April 2002. The patients were asked about taste symptoms before surgery and 2 weeks and 2 years after surgery. The CTN function was also measured with electrogustometry (EGM) at the same time points.
In unilateral section of CTN, 19/32 (59.4%) complained of taste disorder and 11/32 (34.4%) tongue numbness. Most of these taste symptoms disappeared within 2 years although the EGM threshold did not recover. 16/17 patients (94.1%) who used to cook everyday had little difficulty in flavoring dishes. In bilateral section of CTN, the patients had no problem of taste at 2 years after surgery, either.
These findings help explain the potential complications to the patients before surgery, although the number of cases was small in this series.
为前瞻性研究中耳手术中鼓索神经（CTN）切断术后的临床表现及味觉功能恢复情况，对患者进行了主观和客观研究。
2000年1月至2002年4月期间，35例患者接受了单侧（n = 32）或双侧（n = 3）CTN切断手术。询问患者术前、术后2周及2年的味觉症状。同时在相同时间点用电味觉测量法（EGM）测量CTN功能。
单侧CTN切断术中，19/32（59.4%）患者主诉有味觉障碍，11/32（34.4%）患者有舌麻木感。尽管EGM阈值未恢复，但大多数这些味觉症状在2年内消失。16/17（94.1%）过去每天做饭的患者在调味菜肴方面几乎没有困难。双侧CTN切断术后，患者在术后2年也没有味觉问题。
尽管本系列病例数量较少，但这些发现有助于解释术前患者可能出现的并发症。
