RPC10编码一种酵母核RNA聚合酶共有的新型小亚基。
RPC10 encodes a new mini subunit shared by yeast nuclear RNA polymerases.
作者信息
Treich I, Carles C, Riva M, Sentenac A
机构信息
DBCM, Section of Biochemistry and Molecular Genetics, Saclay Research Center, Gif-sur-Yvette, France.
出版信息
Gene Expr. 1992;2(1):31-7.
Abstract
Yeast RNA polymerases A, B, and C share five small subunits, two of which, ABC10 alpha and ABC10 beta, comigrate on SDS polyacrylamide gels. The gene encoding ABC10 alpha, RPC10, was isolated based on microsequence data. RPC10 is a single copy gene localized on chromosome VIII. It codes for a very basic protein of only 70 amino acids, which contains a zinc binding domain of the form CX2CX13CX2C. Deletion of its gene indicated that, despite its very small size, the ABC10 alpha subunit is essential for yeast cell viability. ABC10 alpha and ABC10 beta have little sequence similarity.
摘要
酵母RNA聚合酶A、B和C共有五个小亚基，其中两个，即ABC10α和ABC10β，在SDS聚丙烯酰胺凝胶上迁移率相同。基于微序列数据分离出了编码ABC10α的基因RPC10。RPC10是一个单拷贝基因，定位于第八条染色体上。它编码一种仅由70个氨基酸组成的碱性很强的蛋白质，该蛋白质含有CX2CX13CX2C形式的锌结合结构域。其基因的缺失表明，尽管ABC10α亚基尺寸非常小，但对酵母细胞的生存力至关重要。ABC10α和ABC10β的序列相似性很低。
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本文引用的文献
1
Role of DNA-RNA hybrids in eukaryots 1. Purification of yeast RNA polymerase B.
FEBS Lett. 1972 Mar;21(1):1-6. doi: 10.1016/0014-5793(72)80148-0.
2
One-step gene disruption in yeast.
Methods Enzymol. 1983;101:202-11. doi: 10.1016/0076-6879(83)01015-0.
3
Isolation, structure, and general properties of yeast ribonucleic acid polymerase A (or I).
J Biol Chem. 1974 Sep 25;249(18):5963-70.
4
Vector systems for the expression, analysis and cloning of DNA sequences in S. cerevisiae.
Yeast. 1985 Dec;1(2):83-138. doi: 10.1002/yea.320010202.
5
Yeast RNA polymerase C and its subunits. Specific antibodies as structural and functional probes.
J Biol Chem. 1985 Dec 5;260(28):15304-10.
6
Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases.
Cell. 1985 Sep;42(2):599-610. doi: 10.1016/0092-8674(85)90117-5.
7
Eukaryotic RNA polymerases.
CRC Crit Rev Biochem. 1985;18(1):31-90. doi: 10.3109/10409238509082539.
8
An electrophoretic karyotype for yeast.
Proc Natl Acad Sci U S A. 1985 Jun;82(11):3756-60. doi: 10.1073/pnas.82.11.3756.
9
RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C.
Cell. 1987 Feb 27;48(4):627-37. doi: 10.1016/0092-8674(87)90241-8.
10
Compilation and comparison of the sequence context around the AUG startcodons in Saccharomyces cerevisiae mRNAs.
Nucleic Acids Res. 1987 Apr 24;15(8):3581-93. doi: 10.1093/nar/15.8.3581.
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