Alouf Benjamin, Grigalonis Meg
A.I. DuPont Hospital for Children, Wilmington, DE, USA.
J Natl Med Assoc. 2005 Aug;97(8):1170-3.
In an effort to prevent rickets and vitamin-D deficiency in healthy infants, the American Academy of Pediatrics recommends a supplement of 200 IU per day of vitamin D to all breastfed and nonbreastfed infants unless they consume at least 500 ml per day of vitamin-D-fortified formula or milk. Case reports of infantile vitamin-D-deficient rickets secondary to maternal vitamin-D deficiency have been reported but focused on mothers who had predictable risk factors for such a deficiency. We report on an infant with vitamin-D-deficient rickets who did not have nutritional risk factors and whose mother did not have nutritional or medical risk factors for such a deficiency. We conclude that the current vitamin-D supplementation guidelines be extended to all infants, regardless of feeding volume or source, or at least to all infants born to dark-skinned mothers.
为预防健康婴儿患佝偻病和维生素D缺乏症,美国儿科学会建议,除非婴儿每天摄入至少500毫升添加维生素D的配方奶或牛奶,否则应给所有母乳喂养和非母乳喂养的婴儿每日补充200国际单位的维生素D。已有关于母亲维生素D缺乏继发婴儿维生素D缺乏性佝偻病的病例报告,但这些报告关注的是有此类缺乏症可预测风险因素的母亲。我们报告了一例没有营养风险因素且其母亲也没有此类缺乏症的营养或医学风险因素的维生素D缺乏性佝偻病婴儿。我们得出结论,当前的维生素D补充指南应扩展至所有婴儿,无论喂养量或喂养来源如何,或者至少扩展至所有母亲为深色皮肤的婴儿。