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母乳喂养婴儿维生素 D 缺乏症的预防和治疗:母体补充维生素 D

Maternal supplementation for prevention and treatment of vitamin D deficiency in exclusively breastfed infants.

机构信息

Department of Nursing, St. Catherine University, St. Paul, Minnesota 55105, USA.

出版信息

Breastfeed Med. 2011 Jun;6(3):137-44. doi: 10.1089/bfm.2010.0025. Epub 2010 Oct 29.

Abstract

Current research links newborn and infant vitamin D deficiency with various clinical outcomes, including rickets, failure to thrive, type 1 diabetes, and other immune-related diseases. Breastfed infants are often at a greater risk of developing deficiency due to their mothers' low vitamin D status. Human milk reflects the vitamin D status of the mother and often contains inadequate levels of 25-hydroxyvitamin D for infant nutrition. In 2008 the American Academy of Pediatrics (AAP) recommended 400 IU of vitamin D supplementation of all infants. However, research has indicated low levels of compliance of vitamin D supplementation of breastfed infants and a high incidence of vitamin D deficiency in the United States. Many breastfeeding advocates believe that the AAP's recommendations undermine breastfeeding, implying that human milk is inadequate for infant nutrition. Lactating mothers are also reluctant to add any supplements to their breastmilk. The literature review will examine the effectiveness and safety of maternal vitamin D supplementation for prevention and/or treatment of vitamin D deficiency in breastfed infants and lactating mothers. This method of prevention and intervention provides pediatric providers and certified lactation consultants with an alternative approach for education, counseling, promotion of breastfeeding, and treatment to improve maternal and infant health.

摘要

目前的研究将新生儿和婴儿维生素 D 缺乏与各种临床结果联系起来,包括佝偻病、生长不良、1 型糖尿病和其他与免疫相关的疾病。由于母亲维生素 D 水平低,母乳喂养的婴儿往往面临更大的维生素 D 缺乏风险。人乳反映了母亲的维生素 D 状况,通常含有不足的 25-羟维生素 D 来满足婴儿的营养需求。2008 年,美国儿科学会 (AAP) 建议所有婴儿补充 400IU 的维生素 D。然而,研究表明,母乳喂养的婴儿补充维生素 D 的依从性较低,而且美国维生素 D 缺乏症的发病率较高。许多母乳喂养的倡导者认为,AAP 的建议破坏了母乳喂养,暗示人乳不足以满足婴儿的营养需求。哺乳期母亲也不愿意在母乳中添加任何补充剂。文献综述将检查母亲补充维生素 D 预防和/或治疗母乳喂养婴儿和哺乳期母亲维生素 D 缺乏症的有效性和安全性。这种预防和干预方法为儿科医生和认证的哺乳顾问提供了一种替代方法,用于教育、咨询、促进母乳喂养和治疗,以改善母婴健康。

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