Tezer Hasan, Siklar Zeynep, Dallar Yildiz, Doğankoç Seyda
Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2009 Mar-Apr;51(2):110-5.
Nutritional rickets is re-emerging as a significant health problem among children. We determined the frequency of nutritional rickets and vitamin D deficiency among hospitalized children and the effective factors. During a one-year period, 305 hospitalized children (ages between 0 to 3 years) were evaluated for clinical and biochemical markers of vitamin D deficient rickets and related factors. Twenty-one of them (6.8%) were diagnosed as nutritional vitamin D deficiency and rickets. Most of the children diagnosed were under one year old (16/21, 76.2%). Fourteen vitamin D deficient rachitic children were admitted to the hospital with infectious conditions, and most of them were respiratory tract infection. The rachitic group was compared for statistical significance with the non-rachitic control patients for the data collected. Rachitic children had a lower rate of vitamin D intake. The frequency of malnutrition and anemia and the percentage of covered mothers were higher in the rachitic group than in the control group. Vitamin D deficiency-related rickets is still a common and serious health problem especially in the infancy period. To address this problem, a specific attention should be given to women of reproductive age and in the early infancy period. Initiation of vitamin D supplementation could be offered very early (perhaps after the birth) in children with risk factors.
营养性佝偻病正再度成为儿童中的一个重大健康问题。我们确定了住院儿童中营养性佝偻病和维生素D缺乏的发生率以及相关影响因素。在为期一年的时间里，对305名住院儿童（年龄在0至3岁之间）进行了维生素D缺乏性佝偻病的临床和生化指标以及相关因素的评估。其中21名（6.8%）被诊断为营养性维生素D缺乏和佝偻病。大多数被诊断出的儿童年龄在一岁以下（16/21，76.2%）。14名维生素D缺乏性佝偻病患儿因感染性疾病入院，其中大多数是呼吸道感染。对收集到的数据，将佝偻病组与非佝偻病对照组患者进行统计学显著性比较。佝偻病患儿的维生素D摄入量较低。佝偻病组的营养不良和贫血发生率以及母亲受教育程度的百分比均高于对照组。维生素D缺乏相关的佝偻病仍然是一个常见且严重的健康问题，尤其是在婴儿期。为解决这一问题，应特别关注育龄妇女和婴儿早期。对于有风险因素的儿童，可在很早的时候（可能在出生后）就开始补充维生素D。
