Bousquet Jean, Bousquet Philippe J, Godard Philippe, Daures Jean-Pierre
Clinique des Maladies Respiratoires, Hôpital Arnaud de Villeneuve, CHU Montpellier, 34295- Montpellier-Cedex 05, France.
Bull World Health Organ. 2005 Jul;83(7):548-54.
Asthma is a very common chronic disease that occurs in all age groups and is the focus of various clinical and public health interventions. Both morbidity and mortality from asthma are significant. The number of disability-adjusted life years (DALYs) lost due to asthma worldwide is similar to that for diabetes, liver cirrhosis and schizophrenia. Asthma management plans have, however, reduced mortality and severity in countries where they have been applied. Several barriers reduce the availability, affordability, dissemination and efficacy of optimal asthma management plans in both developed and developing countries. The workplace environment contributes significantly to the general burden of asthma. Patients with occupational asthma have higher rates of hospitalization and mortality than healthy workers. The surveillance of asthma as part of a global WHO programme is essential. The economic cost of asthma is considerable both in terms of direct medical costs (such as hospital admissions and the cost of pharmaceuticals) and indirect medical costs (such as time lost from work and premature death). Direct costs are significant in most countries. In order to reduce costs and improve quality of care, employers and health plans are exploring more precisely targeted ways of controlling rapidly rising health costs. Poor control of asthma symptoms is a major issue that can result in adverse clinical and economic outcomes. A model of asthma costs is needed to aid attempts to reduce them while permitting optimal management of the disease. This paper presents a discussion of the burden of asthma and its socioeconomic implications and proposes a model to predict the costs incurred by the disease.
哮喘是一种非常常见的慢性疾病,可发生于所有年龄组,是各种临床和公共卫生干预措施的重点。哮喘的发病率和死亡率都很高。全球因哮喘而损失的残疾调整生命年(DALYs)数量与糖尿病、肝硬化和精神分裂症的情况相似。然而,在已实施哮喘管理计划的国家,这些计划降低了死亡率和疾病严重程度。在发达国家和发展中国家,有几个障碍降低了最佳哮喘管理计划的可及性、可负担性、推广和效果。工作场所环境对哮喘的总体负担有很大影响。职业性哮喘患者的住院率和死亡率高于健康工人。作为世界卫生组织全球计划的一部分,对哮喘进行监测至关重要。哮喘的经济成本在直接医疗成本(如住院费用和药品成本)和间接医疗成本(如工作时间损失和过早死亡)方面都相当可观。在大多数国家,直接成本都很高。为了降低成本并提高医疗质量,雇主和医疗计划正在探索更具针对性的方法来控制迅速上升的医疗成本。哮喘症状控制不佳是一个可能导致不良临床和经济后果的主要问题。需要一个哮喘成本模型来帮助在允许对该疾病进行最佳管理的同时降低成本。本文讨论了哮喘的负担及其社会经济影响,并提出了一个预测该疾病所产生成本的模型。