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[通过远程心电图进行系统筛查的无症状性心房颤动——对阵发性心房颤动抗凝治疗的相关性]

[Asymptomatic atrial fibrillation with systematic screening using tele-ECG--relevance for anticoagulation in paroxysmal atrial fibrillation].

作者信息

Patten M

机构信息

Universitäres Herzzentrum Hamburg, III. Med. Klinik für Kardiologie und Angiologie, Martinistr. 52, 20246 Hamburg, Germany.

出版信息

Herzschrittmacherther Elektrophysiol. 2005 Sep;16(3):159-64. doi: 10.1007/s00399-005-0475-8.

Abstract

Event recorder monitoring plays an important role in the early detection and diagnosis of rhythm disorders such as atrial fibrillation (AF). In a recent study over 1000 patients with symptomatic paroxysmal AF were followed up by daily and symptom triggered ECG self monitoring. Independent of the presence of antiarrhythmic therapy, the incidence of AF was much higher than expected, since over 50% of AF episodes were asymptomatic. Therefore, patients symptoms are not a reliable surrogate parameter for the detection of AF. Moreover, antiarrhythmic therapy does not totally prevent atrial fibrillation, but raises the risk of silent AF episodes by reducing the mean heart rate. Based on these findings, effective anticoagulation should be taken into consideration in patients with paroxysmal AF independent of antiarrhythmic medication. The decision for anticoagulation with cumarine derivates or aspirin is dependent on the age, underlying diseases, and the individual thromboembolic risk in these patients.

摘要

事件记录仪监测在诸如房颤(AF)等心律失常的早期检测和诊断中发挥着重要作用。在最近一项研究中,对1000多名有症状的阵发性房颤患者进行了每日及症状触发的心电图自我监测随访。无论是否进行抗心律失常治疗,房颤的发生率都远高于预期,因为超过50%的房颤发作是无症状的。因此,患者的症状并非检测房颤的可靠替代参数。此外,抗心律失常治疗并不能完全预防房颤,反而会通过降低平均心率增加无症状房颤发作的风险。基于这些发现,对于阵发性房颤患者,无论是否使用抗心律失常药物,都应考虑进行有效的抗凝治疗。使用香豆素衍生物或阿司匹林进行抗凝的决策取决于这些患者的年龄、基础疾病以及个体血栓栓塞风险。

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