孤立性左主干冠状动脉狭窄与纵隔放疗。
Isolated left main coronary stenosis and mediastinal irradiation.
作者信息
Chinnasami B R, Schwartz R C, Pink S B, Skotnicki R A
机构信息
Department of Medicine, Polyclinic Medical Center, Harrisburg, Pennsylvania 17110.
出版信息
Clin Cardiol. 1992 Jun;15(6):459-61. doi: 10.1002/clc.4960150614.
PMID:1617827
Abstract
This report draws an association between mediastinal irradiation and isolated left main coronary artery stenosis. The report highlights two patients who developed selective left main coronary artery stenosis post mediastinal treatment. In the animal model, it has been shown that high serum cholesterol levels at the time of, or soon after, irradiation are necessary to initiate arteriosclerotic plaque formation.
摘要
本报告阐述了纵隔放疗与孤立性左主干冠状动脉狭窄之间的关联。该报告重点介绍了两名患者，他们在纵隔治疗后出现了选择性左主干冠状动脉狭窄。在动物模型中，研究表明，放疗时或放疗后不久的高血清胆固醇水平是引发动脉粥样硬化斑块形成的必要条件。
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