宠物鸟源新城疫病毒分离株的致病型分析
Pathotyping of Newcastle disease virus isolates from pet birds.
作者信息
Senthuran S, Vijayarani K, Kumanan K, Nainar A M
机构信息
Department of Animal Biotechnology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai 600 007, India.
出版信息
Acta Virol. 2005;49(3):177-82.
Four Newcastle disease virus (NDV) isolates obtained from a pigeon, lory, parrot, and love bird were subjected to biological and molecular characterization. All the isolates were identified as velogenic with intracerebral pathogenicity indices (ICPI) of 1.9-2.0. All the isolates had a 112RRQKRF117 motif in the fusion protein cleavage site (FPCS), typical for pathogenic NDV. Phylogenetic analysis placed the isolates along with a velogenic Indian isolate of Cl group recovered during 1987.
对从鸽子、吸蜜鹦鹉、鹦鹉和情侣鹦鹉中获得的4株新城疫病毒（NDV）分离株进行了生物学和分子特征分析。所有分离株均被鉴定为速发型，脑内致病指数（ICPI）为1.9 - 2.0。所有分离株在融合蛋白裂解位点（FPCS）均具有112RRQKRF117基序，这是致病性NDV的典型特征。系统发育分析将这些分离株与1987年分离的一株Cl组速发型印度分离株归为一类。
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