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Pharmacokinetic and pharmacodynamic data collection in children and neonates. A quiet frontier.

作者信息

Gilman J T, Gal P

机构信息

Clinical Pharmacology Service, Miami Children's Hospital, Florida.

出版信息

Clin Pharmacokinet. 1992 Jul;23(1):1-9. doi: 10.2165/00003088-199223010-00001.

DOI:10.2165/00003088-199223010-00001
PMID:1617855
Abstract
摘要

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Pharmacokinetic and pharmacodynamic data collection in children and neonates. A quiet frontier.
Clin Pharmacokinet. 1992 Jul;23(1):1-9. doi: 10.2165/00003088-199223010-00001.
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Paediatric labelling requirements. Implications for pharmacokinetic studies.儿科标签要求。对药代动力学研究的影响。
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Two-compartment gentamicin pharmacokinetics in premature neonates: a comparison to adults with decreased glomerular filtration rates.
J Pediatr. 1980 Feb;96(2):325-30. doi: 10.1016/s0022-3476(80)80840-7.
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Optimized blood sampling protocols and sequential design of kinetic experiments.
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Phenobarbital and phenytoin in neonatal seizures: metabolism and tissue distribution.
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Learning ability and methylphenidate (Ritalin) plasma concentration in hyperkinetic children. A preliminary investigation.多动症儿童的学习能力与哌甲酯（利他林）血药浓度：一项初步调查
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Safety and transparency of pediatric drug trials.儿科药物试验的安全性与透明度。
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Safety monitoring of drugs receiving pediatric marketing exclusivity.获得儿科市场独占权药物的安全性监测
Pediatrics. 2008 Sep;122(3):e628-33. doi: 10.1542/peds.2008-0585.
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Off-label and unlicensed drug utilization in hospitalized children in Fortaleza, Brazil.巴西福塔莱萨住院儿童的标签外用药和未获许可药物的使用情况。
Eur J Clin Pharmacol. 2008 Nov;64(11):1111-8. doi: 10.1007/s00228-008-0543-1. Epub 2008 Aug 7.
7
Documentation of pediatric drug safety in manufacturers' product monographs: a cross-sectional evaluation of the canadian compendium of pharmaceuticals and specialities.制造商产品说明书中儿科药物安全性的记录：对《加拿大药品和特殊产品汇编》的横断面评估
Paediatr Drugs. 2008;10(3):193-7. doi: 10.2165/00148581-200810030-00007.
8
Population pharmacokinetics of pyrimethamine and sulfadoxine in children treated for congenital toxoplasmosis.乙胺嘧啶和磺胺多辛在接受先天性弓形虫病治疗儿童中的群体药代动力学。
Antimicrob Agents Chemother. 2004 Oct;48(10):3794-800. doi: 10.1128/AAC.48.10.3794-3800.2004.
9
Population pharmacokinetics of arbekacin, vancomycin, and panipenem in neonates.阿贝卡星、万古霉素和帕尼培南在新生儿中的群体药代动力学。
Antimicrob Agents Chemother. 2004 Apr;48(4):1159-67. doi: 10.1128/AAC.48.4.1159-1167.2004.
10
Transdermal reverse iontophoresis of valproate: a noninvasive method for therapeutic drug monitoring.丙戊酸盐的经皮反向离子电渗疗法：一种用于治疗药物监测的非侵入性方法。
Pharm Res. 2003 Sep;20(9):1508-13. doi: 10.1023/a:1025730815971.
J Am Acad Child Psychiatry. 1982 Jan;21(1):27-30. doi: 10.1097/00004583-198201000-00006.
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Psychopharmacology of attention deficit disorder: pharmacokinetic, neuroendocrine, and behavioral measures following acute and chronic treatment with methylphenidate.
Pediatrics. 1982 Jun;69(6):688-94.
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Pharmacokinetics of tobramycin in cystic fibrosis.
J Pediatr. 1982 Feb;100(2):318-21. doi: 10.1016/s0022-3476(82)80664-1.
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Dosing implications of altered gentamicin disposition in patients with cystic fibrosis.
J Pediatr. 1982 Feb;100(2):312-8. doi: 10.1016/s0022-3476(82)80663-x.
8
Distribution of phenobarbital in serum, brain and other organs from pediatric patients.苯巴比妥在儿科患者血清、脑及其他器官中的分布。
Dev Pharmacol Ther. 1984;7(3):153-9. doi: 10.1159/000457158.
9
The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia.氨基糖苷类血浆水平与革兰氏阴性菌血症患者死亡率的关联。
J Infect Dis. 1984 Mar;149(3):443-8. doi: 10.1093/infdis/149.3.443.
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Clinical correlates of methylphenidate blood levels.
Ther Drug Monit. 1984;6(4):379-92. doi: 10.1097/00007691-198412000-00001.