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帕金森病中抑郁症的患病率及治疗

Prevalence and treatment of depression in Parkinson's disease.

作者信息

Veazey Connie, Aki Sahinde Ozlem Erden, Cook Karon F, Lai Eugene C, Kunik Mark E

机构信息

Houston Center for Quality of Care and Utilization Studies, Veterans Affairs Medical Center (152), 2002 Holcombe Blvd., Houston, TX 77030, USA.

出版信息

J Neuropsychiatry Clin Neurosci. 2005 Summer;17(3):310-23. doi: 10.1176/jnp.17.3.310.

DOI:10.1176/jnp.17.3.310
PMID:16179652
Abstract

Parkinson's disease (PD) is a progressive neurological condition with debilitating symptoms, and depression is a common comorbid condition of this disease. The authors review existing literature on the prevalence and treatment of depression in PD. Prevalence estimates of depression vary widely, ranging from 7%-76%. This variation is due to inconsistent methodology. Treatment options for depression in PD include medication therapy, electroconvulsive therapy (ECT), and psychotherapy. There are few randomized controlled trials of these treatment options. The authors argue for more systematic and controlled research examining both the prevalence and treatment of depression in PD.

摘要

帕金森病(PD)是一种具有使人衰弱症状的进行性神经疾病,而抑郁症是这种疾病常见的共病情况。作者回顾了关于帕金森病中抑郁症患病率和治疗的现有文献。抑郁症患病率的估计差异很大,范围从7%到76%。这种差异是由于方法不一致造成的。帕金森病中抑郁症的治疗选择包括药物治疗、电休克疗法(ECT)和心理治疗。这些治疗选择的随机对照试验很少。作者主张进行更系统和可控的研究,以考察帕金森病中抑郁症的患病率和治疗情况。

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